Irida Kastrati, Ph.D.

Affiliations: 
2009 University of Illinois at Chicago, Chicago, IL, United States 
Area:
Pharmaceutical Chemistry
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"Irida Kastrati"
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Gregory Thatcher grad student 2009 University of Illinois, Chicago
 (Mechanisms of estrogen carcinogenesis in human breast epithelial cells.)
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Publications

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Kastrati I, Joosten SEP, Semina SE, et al. (2020) The NFκB pathway promotes tamoxifen tolerance and disease recurrence in estrogen receptor positive breast cancers. Molecular Cancer Research : McR
El-Shennawy L, Dubrovskyi O, Kastrati I, et al. (2017) Coactivation of estrogen receptor and IKK-β induces a dormant metastatic phenotype in ER-positive breast cancer. Cancer Research
Petukhov PA, Abdelkarim H, Neelarapu R, et al. (2017) Design, Synthesis, Molecular Modeling, and Biological Evaluation of Novel Amine-based Histone Deacetylase Inhibitors. Chemmedchem
Srinivasan S, Nwachukwu JC, Bruno NE, et al. (2017) Corrigendum: Full antagonism of the estrogen receptor without a prototypical ligand side chain. Nature Chemical Biology. 13: 691
Srinivasan S, Nwachukwu JC, Bruno NE, et al. (2017) Erratum: Full antagonism of the estrogen receptor without a prototypical ligand side chain. Nature Chemical Biology. 13: 691
Kastrati I, Siklos MI, Brovkovych SD, et al. (2017) A Novel Strategy to Co-target Estrogen Receptor and Nuclear Factor κB Pathways with Hybrid Drugs for Breast Cancer Therapy. Hormones & Cancer
Stender JD, Nwachukwu JC, Kastrati I, et al. (2017) Structural and Molecular Mechanisms of Cytokine-Mediated Endocrine Resistance in Human Breast Cancer Cells. Molecular Cell. 65: 1122-1135.e5
Kastrati I, Delgado-Rivera L, Georgieva G, et al. (2017) Synthesis and Characterization of an Aspirin-fumarate Prodrug that Inhibits NFκB Activity and Breast Cancer Stem Cells. Journal of Visualized Experiments : Jove
Srinivasan S, Nwachukwu JC, Bruno NE, et al. (2016) Full antagonism of the estrogen receptor without a prototypical ligand side chain. Nature Chemical Biology
Kastrati I, Siklos MI, Calderon-Gierszal EL, et al. (2016) Dimethyl Fumarate Inhibits the Nuclear Factor κB Pathway in Breast Cancer Cells by Covalent Modification of p65 Protein. The Journal of Biological Chemistry. 291: 3639-47
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