Laurel K. Mydock, Ph.D.

Affiliations: 
2010 University of Missouri - Saint Louis 
Area:
Organic Chemistry
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"Laurel Mydock"
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Parents

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Alexei V. Demchenko grad student 2010 University of Missouri - Saint Louis
 (The nature of the O-2/O-5 cooperative effect and its role in chemical glycosylation.)
James W. Janetka research scientist 2014- Washington University
 (Fimbrion)
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Publications

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Nachtergaele S, Whalen DM, Mydock LK, et al. (2013) Structure and function of the Smoothened extracellular domain in vertebrate Hedgehog signaling. Elife. 2: e01340
Nachtergaele S, Whalen DM, Mydock LK, et al. (2013) Structure and function of the Smoothened extracellular domain in vertebrate Hedgehog signaling Elife. 2013
Nachtergaele S, Mydock LK, Krishnan K, et al. (2012) Oxysterols are allosteric activators of the oncoprotein Smoothened. Nature Chemical Biology. 8: 211-20
Mydock LK, Kamat MN, Demchenko AV. (2011) Direct synthesis of diastereomerically pure glycosyl sulfonium salts. Organic Letters. 13: 2928-31
Mydock LK, Spilling CD, Demchenko AV. (2011) Concise synthesis of 1,3-di-O-substituted tetrahydropyran derivatives as conformationally stable pyranose mimetics Comptes Rendus Chimie. 14: 301-306
Parameswar AR, Hawkins JA, Mydock LK, et al. (2010) Concise Synthesis of the Unnatural Sphingosine and Psychosine Enantiomer. European Journal of Organic Chemistry. 2010
Premathilake HD, Mydock LK, Demchenko AV. (2010) Superarming common glycosyl donors by simple 2-O-benzoyl-3,4,6-tri-O-benzyl protection. The Journal of Organic Chemistry. 75: 1095-100
Mydock LK, Demchenko AV. (2010) Mechanism of chemical O-glycosylation: from early studies to recent discoveries. Organic & Biomolecular Chemistry. 8: 497-510
Mydock LK, Demchenko AV. (2008) Superarming the S-benzoxazolyl glycosyl donors by simple 2-O-benzoyl-3,4,6-tri-O-benzyl protection. Organic Letters. 10: 2103-6
Mydock LK, Demchenko AV. (2008) Application of the superarmed glycosyl donor to chemoselective oligosaccharide synthesis. Organic Letters. 10: 2107-10
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