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Lori L. O'Brien, Ph.D.

Affiliations: 
2008 University of Wisconsin, Madison, Madison, WI 
Area:
Cell Biology
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Christiane Wiese grad student 2008 UW Madison
 (The role of Targeting Protein for Xklp2 (TPX2) in nuclear assembly and organization.)

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Publications

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Gerlach GF, Imseis ZH, Cooper SL, et al. (2023) Mapping of the podocin proximity-dependent proteome reveals novel components of the kidney podocyte foot process. Frontiers in Cell and Developmental Biology. 11: 1195037
O'Brien LL, Combes AN, Short KM, et al. (2018) Wnt11 directs nephron progenitor polarity and motile behavior ultimately determining nephron endowment. Elife. 7
O'Brien LL, Guo Q, Bahrami-Samani E, et al. (2018) Transcriptional regulatory control of mammalian nephron progenitors revealed by multi-factor cistromic analysis and genetic studies. Plos Genetics. 14: e1007181
O'Brien LL, Guo Q, Lee Y, et al. (2016) Differential regulation of mouse and human nephron progenitors by the Six family of transcriptional regulators. Development (Cambridge, England). 143: 595-608
Park JS, Ma W, O'Brien LL, et al. (2012) Six2 and Wnt regulate self-renewal and commitment of nephron progenitors through shared gene regulatory networks. Developmental Cell. 23: 637-51
O'Brien LL, Grimaldi M, Kostun Z, et al. (2011) Wt1a, Foxc1a, and the Notch mediator Rbpj physically interact and regulate the formation of podocytes in zebrafish. Developmental Biology. 358: 318-30
Woolner S, O'Brien LL, Wiese C, et al. (2008) Myosin-10 and actin filaments are essential for mitotic spindle function Journal of Cell Biology. 182: 77-88
Wiese C, O'Brien LL. (2006) What's so Bor(a)ing about Aurora-A activation? Developmental Cell. 11: 133-4
O'Brien LL, Wiese C. (2006) TPX2 is required for postmitotic nuclear assembly in cell-free Xenopus laevis egg extracts. The Journal of Cell Biology. 173: 685-94
O'Brien LL, Albee AJ, Liu L, et al. (2005) The Xenopus TACC homologue, maskin, functions in mitotic spindle assembly. Molecular Biology of the Cell. 16: 2836-47
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