Philip A. Cole

Affiliations: 
1996-1999 Bioorganic Chemistry Rockefeller University, New York, NY, United States 
 1999- Pharmacology and Molecular Sciences Johns Hopkins University, Baltimore, MD 
Area:
Pharmacology, Biochemistry
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"Philip Cole"
Bio:

http://www.hopkinsmedicine.org/institute_basic_biomedical_sciences/research_centers/high_throughput_biology_hit/technology_center_networks_pathways/pdfs/cole_biosketch_8-08.pdf

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Publications

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Liu R, Ren X, Park YE, et al. (2024) Nuclear GTPSCS functions as a lactyl-CoA synthetase to promote histone lactylation and gliomagenesis. Cell Metabolism
Whedon SD, Lee K, Wang ZA, et al. (2024) Circular Engineered Sortase for Interrogating Histone H3 in Chromatin. Journal of the American Chemical Society
Whedon SD, Lee K, Wang ZA, et al. (2024) A circular engineered sortase for interrogating histone H3 in chromatin. Biorxiv : the Preprint Server For Biology
Abeywardana MY, Whedon SD, Lee K, et al. (2024) Multifaceted regulation of Sirtuin 2 (Sirt2) Deacetylase Activity. The Journal of Biological Chemistry. 107722
Lee K, Barone M, Waterbury AL, et al. (2024) Uncoupling histone modification crosstalk by engineering lysine demethylase LSD1. Nature Chemical Biology
Yeo MJ, Zhang O, Xie X, et al. (2024) Asymmetric Engagement of Dimeric CRL3 by the Molecular Glue UM171 Licenses Degradation of HDAC1/2 Complexes. Biorxiv : the Preprint Server For Biology
Xie X, Zhang O, Yeo MJR, et al. (2024) KBTBD4 Cancer Hotspot Mutations Drive Neomorphic Degradation of HDAC1/2 Corepressor Complexes. Biorxiv : the Preprint Server For Biology
Wright KM, Nathan S, Jiang H, et al. (2024) NEDD4L intramolecular Interactions regulate its auto- and substrate Na1.5 ubiquitination. The Journal of Biological Chemistry. 105715
Wright KM, Jiang H, Xia W, et al. (2023) The C-Terminal of Na1.7 Is Ubiquitinated by NEDD4L. Acs Bio & Med Chem Au. 3: 516-527
Wang ZA, Markert JW, Whedon SD, et al. (2023) Structural Basis of Sirtuin 6-Catalyzed Nucleosome Deacetylation. Journal of the American Chemical Society
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