☰ Chemistry Tree

Philip A. Cole

Affiliations:	1996-1999	Bioorganic Chemistry	Rockefeller University, New York, NY, United States
	1999-	Pharmacology and Molecular Sciences	Johns Hopkins University, Baltimore, MD

Area:

Pharmacology, Biochemistry

Google:

Bio:

http://www.hopkinsmedicine.org/institute_basic_biomedical_sciences/research_centers/high_throughput_biology_hit/technology_center_networks_pathways/pdfs/cole_biosketch_8-08.pdf

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Parents

Samuel J. Danishefsky	research assistant	1983-1984	Yale
(undergraduate student)
Alan Rushton Battersby	research assistant	1984-1985	Cambridge
(Churchill Scholar)
Cecil H. Robinson	grad student	1985-1991	Johns Hopkins Medical School
Christopher T. Walsh	post-doc	1993-1996	Harvard Medical School

Children

Kara A. Scheibner	grad student	2004	Johns Hopkins
Yingfeng Qiao	grad student	2006	Johns Hopkins
Aliya C. Hines	grad student	2007	Johns Hopkins
Jeffrey C. Culhane	grad student	2008	Johns Hopkins
Erin M. Bowers	grad student	2011	Johns Hopkins
Mary K. Tarrant	grad student	2011	Johns Hopkins
Blair C. Dancy	grad student	2012	Johns Hopkins
Maria I. Martinez Ferrando	grad student	2012	Johns Hopkins
Gai Yan	grad student	2012	Johns Hopkins
Zhipeng Aaron Wang	post-doc		Harvard Medical School - Brigham and Women's Hospital
Eunju Nam	post-doc	2022-	Brigham and Women's Hospital / Harvard Medical School
Keykavous Parang	post-doc	1999-2000	Johns Hopkins
Paul R. Thompson	post-doc	2000-2003	Johns Hopkins Medical School
William J. Drury	post-doc	2004-2006	The Johns Hopkins University, school of medicine
Rong Huang	post-doc	2007-2011	Johns Hopkins Medical School

Collaborators

David Cowburn	collaborator
Sandra B. Gabelli	collaborator	2012-	Johns Hopkins Medical School/HHMI

BETA: Related publications

Publications

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Wang ZA, Markert JW, Whedon SD, et al. (2023) Structural Basis of Sirtuin 6-Catalyzed Nucleosome Deacetylation. Journal of the American Chemical Society
Lee K, Whedon SD, Wang ZA, et al. (2022) Distinct biochemical properties of the class I histone deacetylase complexes. Current Opinion in Chemical Biology. 70: 102179
Jiang H, Chiang CY, Chen Z, et al. (2022) Enzymatic Analysis of WWP2 E3 Ubiquitin Ligase Using Protein Microarrays Identifies Autophagy-Related Substrates. The Journal of Biological Chemistry. 101854
Wang ZA, Whedon SD, Wu M, et al. (2022) Histone H2B Deacylation Selectivity: Exploring Chromatin's Dark Matter with an Engineered Sortase. Journal of the American Chemical Society
Salguero AL, Chen M, Balana AT, et al. (2021) Multifaceted Regulation of Akt by Diverse C-Terminal Post-translational Modifications. Acs Chemical Biology
Pujari SS, Wu M, Thomforde J, et al. (2021) Site-Specific 5-Formyl Cytosine Mediated DNA-Histone Cross-Links: Synthesis and Polymerase Bypass by Human DNA Polymerase η. Angewandte Chemie (International Ed. in English)
Dempsey DR, Viennet T, Iwase R, et al. (2021) The structural basis of PTEN regulation by multi-site phosphorylation. Nature Structural & Molecular Biology. 28: 858-868
Shiota H, Alekseyenko AA, Wang ZA, et al. (2021) Chemical screen identifies diverse and novel HDAC inhibitors as repressors of NUT function: implications for NUT carcinoma pathogenesis and treatment. Molecular Cancer Research : McR
Chu N, Viennet T, Bae H, et al. (2020) The Structural Determinants of PH Domain-Mediated Regulation of Akt Revealed by Segmental Labeling. Elife. 9
Wang ZA, Cole PA. (2020) The Chemical Biology of Reversible Lysine Post-translational Modifications. Cell Chemical Biology

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