Charles N. Serhan

Affiliations: 
Harvard University, Cambridge, MA, United States 
Area:
Pharmacology, Immunology, Biochemistry
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"Charles Serhan"
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Publications

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Reinertsen AF, Libreros S, Nshimiyimana R, et al. (2023) Metabolization of Resolvin E4 by ω-Oxidation in Human Neutrophils: Synthesis and Biological Evaluation of 20-Hydroxy-Resolvin E4 (20-OH-RvE4). Acs Pharmacology & Translational Science. 6: 1898-1908
Rao Z, Brunner E, Giszas B, et al. (2023) Glucocorticoids regulate lipid mediator networks by reciprocal modulation of 15-lipoxygenase isoforms affecting inflammation resolution. Proceedings of the National Academy of Sciences of the United States of America. 120: e2302070120
Libreros S, Nshimiyimana R, Lee B, et al. (2023) Infectious Neutrophil deployment is regulated by Resolvin D4. Blood
Serhan CN, Chiang N. (2023) Resolvins and cysteinyl-containing pro-resolving mediators activate resolution of infectious inflammation and tissue regeneration. Prostaglandins & Other Lipid Mediators. 166: 106718
Serhan CN, Sulciner ML. (2023) Resolution medicine in cancer, infection, pain and inflammation: are we on track to address the next Pandemic? Cancer Metastasis Reviews. 1-5
Nshimiyimana R, Glynn SJ, Serhan CN, et al. (2022) Stereocontrolled total synthesis of Resolvin D4 and 17()-Resolvin D4. Organic & Biomolecular Chemistry
Vidar Hansen T, Serhan CN. (2022) Protectins: Their biosynthesis, metabolism and structure-functions. Biochemical Pharmacology. 206: 115330
Nshimiyimana R, Lam TF, Aggarwal S, et al. (2022) First stereoselective total synthesis of 4(),5()-oxido-17()-hydroxy-6(),8(),10(),13(),15(),19()-docosahexaenoic acid, the biosynthetic precursor of resolvins D3 and D4. Rsc Advances. 12: 11613-11618
Serhan CN, Libreros S, Nshimiyimana R. (2022) E-series resolvin metabolome, biosynthesis and critical role of stereochemistry of specialized pro-resolving mediators (SPMs) in inflammation-resolution: Preparing SPMs for long COVID-19, human clinical trials, and targeted precision nutrition. Seminars in Immunology. 101597
Miek L, Jordan PM, Günther K, et al. (2022) Staphylococcus aureus controls eicosanoid and specialized pro-resolving mediator production via lipoteichoic acid. Immunology
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