Jane V. Aldrich

2001-2015 Medicinal Chemistry University of Kansas, Lawrence, KS, United States 
 2015- University of Florida, Gainesville, Gainesville, FL, United States 
Pharmaceutical Chemistry
"Jane Aldrich"

DOI: 10.1021/jm00372a005

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Raymond E. Counsell grad student 1983 University of Michigan
 (Synthesis and Evaluation of 19-Aza and 19-Amino Androstenedione Analogs as Potential Aromatase Inhibitors.)
Philip S. Portoghese post-doc 1984-1986 UMN
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Fang WJ, Murray TF, Aldrich JV. (2017) Design, synthesis, and opioid activity of arodyn analogs cyclized by ring-closing metathesis involving Tyr(allyl). Bioorganic & Medicinal Chemistry
Joshi AA, Murray TF, Aldrich JV. (2017) Alanine scan of the opioid peptide dynorphin B amide. Biopolymers
Khaliq T, Williams TD, Senadheera SN, et al. (2016) Development of a robust, sensitive and selective liquid chromatography-tandem mass spectrometry assay for the quantification of the novel macrocyclic peptide kappa opioid receptor antagonist [D-Trp]CJ-15,208 in plasma and application to an initial pharmacokinetic study. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 1028: 11-15
Sirohi S, Aldrich JV, Walker BM. (2016) Species differences in the effects of the κ-opioid receptor antagonist zyklophin. Alcohol (Fayetteville, N.Y.). 51: 43-9
Huang P, Yakovleva T, Aldrich JV, et al. (2016) Two short-acting kappa opioid receptor antagonists (zyklophin and LY2444296) exhibited different behavioral effects from the long-acting antagonist norbinaltorphimine in mouse anxiety tests. Neuroscience Letters
Joshi A, Murray TF, Aldrich JV. (2015) Structure-Activity Relationships of the Peptide Kappa Opioid Receptor Antagonist Zyklophin. Journal of Medicinal Chemistry
Aldrich JV, Senadheera SN, Ross NC, et al. (2014) Alanine analogues of [D-Trp]CJ-15,208: novel opioid activity profiles and prevention of drug- and stress-induced reinstatement of cocaine-seeking behaviour. British Journal of Pharmacology. 171: 3212-22
Dimattio KM, Yakovleva TV, Aldrich JV, et al. (2014) Zyklophin, a short-acting kappa opioid antagonist, induces scratching in mice. Neuroscience Letters. 563: 155-9
Mukhopadhyay A, Tabanor K, Chaguturu R, et al. (2013) Targeting inhibitor 2 of protein phosphatase 2A as a therapeutic strategy for prostate cancer treatment. Cancer Biology & Therapy. 14: 962-72
Eans SO, Ganno ML, Reilley KJ, et al. (2013) The macrocyclic tetrapeptide [D-Trp]CJ-15,208 produces short-acting κ opioid receptor antagonism in the CNS after oral administration. British Journal of Pharmacology. 169: 426-36
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