Russell Thomson, Ph.D.

Affiliations: 
2009 Basic Medical Science New York University, New York, NY, United States 
Area:
Parasitology Biology, Biomedical Engineering, Biochemistry
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"Russell Thomson"
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Jayne Raper grad student 2009 NYU
 (The identification, cloning and characterization of baboon trypanosome lytic factor.)
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Publications

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Schaub C, Lee P, Racho-Jansen A, et al. (2021) Coiled-coil binding of the leucine zipper domains of APOL1 is necessary for the open cation channel conformation. The Journal of Biological Chemistry. 101009
Pant J, Giovinazzo JA, Tuka LS, et al. (2021) Apolipoproteins L1-6 share key cation channel-regulating residues but have different membrane insertion and ion conductance properties. The Journal of Biological Chemistry. 100951
Schaub C, Verdi J, Lee P, et al. (2020) Cation channel conductance and pH gating of the innate immunity factor APOL1 is governed by pore lining residues within the C-terminal domain. The Journal of Biological Chemistry
Giovinazzo JA, Thomson RP, Khalizova N, et al. (2020) Apolipoprotein L-1 renal risk variants form active channels at the plasma membrane driving cytotoxicity. Elife. 9
Verdi J, Zipkin R, Hillman E, et al. (2020) Inducible Germline IgMs Bridge Trypanosome Lytic Factor Assembly and Parasite Recognition. Cell Host & Microbe
Verdi J, Schaub C, Thomson R, et al. (2020) All You Ever Wanted to Know About APOL1 and TLFs and Did Not Dare Ask. Methods in Molecular Biology (Clifton, N.J.). 2116: 463-483
Cooper A, Capewell P, Clucas C, et al. (2016) A Primate APOL1 Variant That Kills Trypanosoma brucei gambiense. Plos Neglected Tropical Diseases. 10: e0004903
Thomson R, Finkelstein A. (2015) Human trypanolytic factor APOL1 forms pH-gated cation-selective channels in planar lipid bilayers: relevance to trypanosome lysis. Proceedings of the National Academy of Sciences of the United States of America. 112: 2894-9
Thomson R, Genovese G, Canon C, et al. (2014) Evolution of the primate trypanolytic factor APOL1. Proceedings of the National Academy of Sciences of the United States of America. 111: E2130-9
Thomson R, Molina-Portela P, Mott H, et al. (2009) Hydrodynamic gene delivery of baboon trypanosome lytic factor eliminates both animal and human-infective African trypanosomes. Proceedings of the National Academy of Sciences of the United States of America. 106: 19509-14
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