Orrette R. Wauchope, Ph.D.

Affiliations: 
2011 Chemistry University of Maryland, Baltimore County, Baltimore, MD, United States 
Area:
Pharmaceutical Chemistry, Biochemistry, Organic Chemistry
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"Orrette Wauchope"
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Katherine L. Seley-Radtke grad student 2011 UMBC
 (Structural explorations to the purine scaffold for use in nucleoside drug design.)
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Publications

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Galligan JJ, Kingsley PJ, Wauchope O, et al. (2016) Quantitative Analysis and Discovery of Lysine and Arginine Modifications (QuARKMod). Analytical Chemistry
Shuck SC, Wauchope OR, Rose KL, et al. (2014) Protein modification by adenine propenal. Chemical Research in Toxicology. 27: 1732-42
Wauchope OR, Velasquez M, Seley-Radtke K. (2012) Synthetic Routes to a Series of Proximal and Distal 2'-Deoxy Fleximers. Synthesis. 44: 3496-3504
Wauchope OR, Johnson C, Krishnamoorthy P, et al. (2012) Synthesis and biological evaluation of a series of thieno-expanded tricyclic purine 2'-deoxy nucleoside analogues. Bioorganic & Medicinal Chemistry. 20: 3009-15
Manvilla BA, Wauchope O, Seley-Radtke KL, et al. (2011) NMR studies reveal an unexpected binding site for a redox inhibitor of AP endonuclease 1. Biochemistry. 50: 10540-9
Wauchope OR, Tomney MJ, Pepper JL, et al. (2010) Tricyclic 2'-C-modified nucleosides as potential anti-HCV therapeutics. Organic Letters. 12: 4466-9
Zhang Z, Wauchope OR, Seley-Radtke KL. (2008) Mechanistic studies in the synthesis of a series of thieno-expanded xanthosine and guanosine nucleosides. Tetrahedron. 64: 10791-10797
Seley-Radtke KL, Zhang Z, Wauchope OR, et al. (2008) Hetero-expanded purine nucleosides. Design, synthesis and preliminary biological activity. Nucleic Acids Symposium Series (2004). 635-6
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