Louise Hecker, Ph.D.

Affiliations: 
2008 University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Biomedical Engineering
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Bradford G. Orr grad student 2008 University of Michigan
 (Development of functional bioengineered muscle models and a novel micro-perfusion system.)
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Publications

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Kato K, Chang EH, Chen Y, et al. (2020) MUC1 contributes to goblet cell metaplasia and MUC5AC expression in response to cigarette smoke in vivo. American Journal of Physiology. Lung Cellular and Molecular Physiology
Kato K, Hecker L. (2020) NADPH oxidases: Pathophysiology and therapeutic potential in age-associated pulmonary fibrosis. Redox Biology. 101541
Kato K, Logsdon NJ, Shin YJ, et al. (2020) Impaired Myofibroblast Dedifferentiation Contributes to Non-Resolving Fibrosis in Aging. American Journal of Respiratory Cell and Molecular Biology
Hecker L. (2017) Mechanisms and Consequences of Oxidative Stress in Lung Disease: Therapeutic Implications for an Aging Populace. American Journal of Physiology. Lung Cellular and Molecular Physiology
Ding Q, Subramanian I, Luckhardt TR, et al. (2017) Focal Adhesion Kinase Signaling Determines the Fate of Lung Epithelial Cells in Response to TGF-β. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00121.2016
Palumbo S, Shin YJ, Ahmad K, et al. (2017) Dysregulated Nox4 ubiquitination contributes to redox imbalance and age-related severity of acute lung injury. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00305.2016
Wang T, Mathew B, Wu X, et al. (2016) Nonmuscle myosin light chain kinase activity modulates radiation-induced lung injury. Pulmonary Circulation. 6: 234-9
Hecker L, Thannickal VJ. (2016) Getting to the core of fibrosis: targeting redox imbalance in aging. Annals of Translational Medicine. 4: 93
Hecker L, Logsdon NJ, Kurundkar D, et al. (2014) Reversal of persistent fibrosis in aging by targeting Nox4-Nrf2 redox imbalance. Science Translational Medicine. 6: 231ra47
Bernard K, Hecker L, Luckhardt TR, et al. (2014) NADPH oxidases in lung health and disease. Antioxidants & Redox Signaling. 20: 2838-53
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