Nathan A. Wigner, Ph.D.

Affiliations: 
2009 Boston University, Boston, MA, United States 
Area:
Biochemistry
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Louis C. Gerstenfeld grad student 2009 Boston University
 (Regulation of aggrecan gene promoter during endochondral bone formation and fracture repair.)
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Publications

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Al-Sebaei MO, Daukss DM, Belkina AC, et al. (2014) Role of Fas and Treg cells in fracture healing as characterized in the fas-deficient (lpr) mouse model of lupus. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 29: 1478-91
Wigner NA, Soung do Y, Einhorn TA, et al. (2013) Functional role of Runx3 in the regulation of aggrecan expression during cartilage development. Journal of Cellular Physiology. 228: 2232-42
Carroll SH, Wigner NA, Kulkarni N, et al. (2012) A2B adenosine receptor promotes mesenchymal stem cell differentiation to osteoblasts and bone formation in vivo. The Journal of Biological Chemistry. 287: 15718-27
Wigner NA, Kulkarni N, Yakavonis M, et al. (2012) Urine matrix metalloproteinases (MMPs) as biomarkers for the progression of fracture healing. Injury. 43: 274-8
Bauzá G, Miller G, Kaseje N, et al. (2011) The effects of injury magnitude on the kinetics of the acute phase response. The Journal of Trauma. 70: 948-53
Salisbury Palomares KT, Gerstenfeld LC, Wigner NA, et al. (2010) Transcriptional profiling and biochemical analysis of mechanically induced cartilaginous tissues in a rat model. Arthritis and Rheumatism. 62: 1108-18
Wigner NA, Luderer HF, Cox MK, et al. (2010) Acute phosphate restriction leads to impaired fracture healing and resistance to BMP-2. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 25: 724-33
Carroll SH, Wigner NA, Kulkarni N, et al. (2010) New Regulatory Mechanisms of Bone Marrow Mesenchymal Stem Cell Differentiation Involving An Adenosine Receptor. Blood. 116: 2584-2584
Bais M, McLean J, Sebastiani P, et al. (2009) Transcriptional analysis of fracture healing and the induction of embryonic stem cell-related genes. Plos One. 4: e5393
Bais MV, Wigner N, Young M, et al. (2009) BMP2 is essential for post natal osteogenesis but not for recruitment of osteogenic stem cells. Bone. 45: 254-66
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