Trevor M. Penning

Pharmacology, Biochemistry & Biophysics University of Pennsylvania School of Medicine, Philadelphia, PA, United States 
enzymology of steroid hormones
"Trevor M. Penning"

DOI: 10.1021/cr000049n
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Joseph Martin Jez grad student 1998 Penn
Nisha T. Palackal grad student 2002 Penn
Vladi V. Heredia grad student 2004 Penn
Lawrence M. Szewczuk grad student 2004 Penn
Amy M. Quinn grad student 2008 Penn
Jason E. Drury grad student 2009 Penn
Carol A. Shultz Terkhorn grad student 2009 Penn
Adegoke Adeniji post-doc Penn
Daniel Tamae post-doc 2011-2016 Penn
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Asangani I, Blair IA, Van Duyne G, et al. (2021) Using Biochemistry & Biophysics to Extinguish Androgen Receptor Signaling in Prostate Cancer. The Journal of Biological Chemistry. 100240
Murray JR, Mesaros CA, Arlt VM, et al. (2019) Correction to "Role of Human Aldo-Keto Reductases in the Metabolic Activation of the Carcinogenic Air Pollutant 3-Nitrobenzanthrone". Chemical Research in Toxicology
Chen M, Wangtrakuldee P, Zang T, et al. (2019) Human and murine steroid 5β-reductases (AKR1D1 and AKR1D4): insights into the role of the catalytic glutamic acid. Chemico-Biological Interactions
Verma K, Zang T, Penning TM, et al. (2019) Potent and Highly Selective Aldo-Keto Reductase 1C3 (AKR1C3) Inhibitors Act as Chemotherapeutic Potentiators in Acute Myeloid Leukemia and T-Cell Acute Lymphoblastic Leukemia. Journal of Medicinal Chemistry
Wangtrakuldee P, Adeniji AO, Zang T, et al. (2019) A 3-(4-Nitronaphthen-1-yl) amino-benzoate analog as a Bifunctional AKR1C3 Inhibitor with AR Antagonist Activity: Head to Head Comparison with Other Advanced AKR1C3 Targeted Therapeutics. The Journal of Steroid Biochemistry and Molecular Biology
Murray JR, Mesaros CA, Arlt VM, et al. (2018) Role of Human Aldo-Keto Reductases in the Metabolic Activation of the Carcinogenic Air Pollutant 3-Nitrobenzanthrone. Chemical Research in Toxicology
Mostaghel EA, Zhang A, Hernandez S, et al. (2018) Contribution of Adrenal Glands to Intra-tumor Androgens and Growth of Castration Resistant Prostate Cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research
Penning TM, Wangtrakuldee P, Auchus RJ. (2018) Structural and Functional Biology of Aldo-Keto Reductase Steroid Transforming Enzymes. Endocrine Reviews
Verma K, Gupta N, Zang T, et al. (2018) AKR1C3 Inhibitor KV-37 Exhibits Antineoplastic Effects and Potentiates Enzalutamide in Combination Therapy in Prostate Adenocarcinoma Cells. Molecular Cancer Therapeutics
Huang J, Liu Y, Vitale S, et al. (2017) On meta- and mega-analyses for gene-environment interactions. Genetic Epidemiology
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