Samuel F. Bakhoum, Ph.D.
Affiliations: | 2009 | Biochemistry | Dartmouth College, Hanover, NH, United States |
Area:
Cell BiologyGoogle:
"Samuel Bakhoum"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Duane A. Compton | grad student | 2009 | Dartmouth | |
| (Mechanisms of chromosomal instability in cancer.) | ||||
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Publications
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| Di Bona M, Bakhoum SF. (2024) Micronuclei and Cancer. Cancer Discovery. 14: 214-226 |
| Agustinus AS, Al-Rawi D, Dameracharla B, et al. (2023) Epigenetic dysregulation from chromosomal transit in micronuclei. Nature |
| Lin YF, Hu Q, Mazzagatti A, et al. (2023) Mitotic clustering of pulverized chromosomes from micronuclei. Nature |
| Bakhoum SF. (2023) Targeting the undruggable. Science (New York, N.Y.). 380: 47 |
| Kimmel GJ, Beck RJ, Yu X, et al. (2023) Intra-tumor heterogeneity, turnover rate and karyotype space shape susceptibility to missegregation-induced extinction. Plos Computational Biology. 19: e1010815 |
| Agustinus AS, Bakhoum S. (2022) Biochemical, genomic, and epigenomic profiling of isolated cancer cell lines' micronuclei. Methods in Cell Biology. 172: 51-66 |
| Bakhoum SF. (2022) cGAS-STING and the deadly CIN: how chronic inflammation represents a therapeutic vulnerability in chromosomally unstable cancers. Trends in Cancer |
| Al-Rawi DH, Bakhoum SF. (2022) Chromosomal instability as a source of genomic plasticity. Current Opinion in Genetics & Development. 74: 101913 |
| Bakhoum MF, Francis JH, Agustinus A, et al. (2021) Loss of polycomb repressive complex 1 activity and chromosomal instability drive uveal melanoma progression. Nature Communications. 12: 5402 |
| Venkatesan S, Angelova M, Puttick C, et al. (2021) Induction of APOBEC3 exacerbates DNA replication stress and chromosomal instability in early breast and lung cancer evolution. Cancer Discovery |