Jacqueline C. Shultz, Ph.D.
Affiliations: | 2009 | Biochemistry | Virginia Commonwealth University, Richmond, VA, United States |
Area:
Molecular Biology, BiochemistryGoogle:
"Jacqueline Shultz"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Charles E. Chalfant | grad student | 2009 | VCU | |
| (The regulation of alternative splicing by oncogenic signaling pathways.) | ||||
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Publications
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| Shapiro BA, Vu NT, Shultz MD, et al. (2016) Melanoma differentiation associated gene 7/IL-24 exerts cytotoxic effects by altering the alternative splicing of Bcl-x pre-mRNA via the SRC/PKCδ signaling axis. The Journal of Biological Chemistry |
| Barbour SE, Nguyen PT, Park M, et al. (2015) Group VIA Phospholipase A2 (iPLA2β) Modulates Bcl-x 5'-Splice Site Selection and Suppresses Anti-apoptotic Bcl-x(L) in β-Cells. The Journal of Biological Chemistry. 290: 11021-31 |
| Vu NT, Park MA, Shultz JC, et al. (2013) HnRNP U enhances caspase-9 splicing and is modulated by AKT-dependent phosphorylation of hnRNP L Journal of Biological Chemistry. 288: 8575-8584 |
| Shultz JC, Vu N, Shultz MD, et al. (2012) The proto-oncogene PKCι regulates the alternative splicing of Bcl-x Pre-mRNA Molecular Cancer Research. 10: 660-669 |
| Shultz JC, Chalfant CE. (2012) The flip-flop HuR: part of the problem or the solution in fighting cancer? The Journal of Clinical Investigation. 122: 16-9 |
| Shultz JC, Goehe RW, Murudkar CS, et al. (2011) SRSF1 regulates the alternative splicing of caspase 9 via a novel intronic splicing enhancer affecting the chemotherapeutic sensitivity of non-small cell lung cancer cells. Molecular Cancer Research : McR. 9: 889-900 |
| Shultz JC, Chalfant CE. (2011) Caspase 9b: a new target for therapy in non-small-cell lung cancer. Expert Review of Anticancer Therapy. 11: 499-502 |
| Shultz JC, Goehe RW, Wijesinghe DS, et al. (2010) Alternative splicing of caspase 9 is modulated by the phosphoinositide 3-kinase/Akt pathway via phosphorylation of SRp30a. Cancer Research. 70: 9185-96 |
| Goehe RW, Shultz JC, Murudkar C, et al. (2010) hnRNP L regulates the tumorigenic capacity of lung cancer xenografts in mice via caspase-9 pre-mRNA processing. The Journal of Clinical Investigation. 120: 3923-39 |
| Shultz JC, Chalfant CE. (2007) Emetine and the alternative splicing of Bcl-X: where to next? Chemistry & Biology. 14: 1313-4 |