Travis S. Hughes, Ph.D.

Affiliations: 
2008 Molecular, Cellular and Developmental Biology University of Colorado, Boulder, Boulder, CO, United States 
Area:
Molecular Biology, General Biology, Medicine and Surgery
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"Travis Hughes"
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Leslie A. Leinwand grad student 2008 CU Boulder
 (Naked plasmid DNA as a vector for delivery of genes to the intrathecal space: Expression and immune response.)
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Publications

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Burton MD, Tillu DV, Mazhar K, et al. (2017) Pharmacological activation of AMPK inhibits incision-evoked mechanical hypersensitivity and the development of hyperalgesic priming in mice. Neuroscience
Hughes T, Kim-Howard X, Kelly JA, et al. (2011) Fine-mapping and transethnic genotyping establish IL2/IL21 genetic association with lupus and localize this genetic effect to IL21. Arthritis and Rheumatism. 63: 1689-97
Hutchinson MR, Zhang Y, Shridhar M, et al. (2010) Evidence that opioids may have toll-like receptor 4 and MD-2 effects. Brain, Behavior, and Immunity. 24: 83-95
Sloane E, Langer S, Jekich B, et al. (2009) Immunological priming potentiates non-viral anti-inflammatory gene therapy treatment of neuropathic pain. Gene Therapy. 16: 1210-22
Hughes TS, Langer SJ, Virtanen SI, et al. (2009) Immunogenicity of intrathecal plasmid gene delivery: cytokine release and effects on transgene expression. The Journal of Gene Medicine. 11: 782-90
Soderquist RG, Milligan ED, Sloane EM, et al. (2009) PEGylation of brain-derived neurotrophic factor for preserved biological activity and enhanced spinal cord distribution. Journal of Biomedical Materials Research. Part A. 91: 719-29
Hughes TS, Langer SJ, Johnson KW, et al. (2009) Intrathecal injection of naked plasmid DNA provides long-term expression of secreted proteins. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 88-94
Milligan ED, Soderquist RG, Malone SM, et al. (2006) Intrathecal polymer-based interleukin-10 gene delivery for neuropathic pain. Neuron Glia Biology. 2: 293-308
Milligan ED, Sloane EM, Langer SJ, et al. (2006) Repeated intrathecal injections of plasmid DNA encoding interleukin-10 produce prolonged reversal of neuropathic pain. Pain. 126: 294-308
Langer SJ, Busha D, Milligan ED, et al. (2006) 261. In Vivo Over-Expression of Fractalkine, a Putative Neuron-to-Glia Signal, To Characterize Underlying Mechanisms of Neuropathic Pain Molecular Therapy. 13: S100
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