Larry A. Feig

Biochemistry Sackler School of Graduate Biomedical Sciences (Tufts University) 
Biochemistry, Oncology, Pathology
"Larry Feig"
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Uzturk BG, Jin SX, Rubin B, et al. (2015) RasGRF1 regulates the hypothalamic-pituitary-adrenal axis specifically in early-adolescent female mice. The Journal of Endocrinology. 227: 227-38
Darcy MJ, Jin SX, Feig LA. (2014) R-Ras contributes to LTP and contextual discrimination. Neuroscience. 277: 334-42
Darcy MJ, Trouche S, Jin SX, et al. (2014) Ras-GRF2 mediates long-term potentiation, survival, and response to an enriched environment of newborn neurons in the hippocampus. Hippocampus. 24: 1317-29
Jin SX, Bartolome C, Arai JA, et al. (2014) Domain contributions to signaling specificity differences between Ras-guanine nucleotide releasing factor (Ras-GRF) 1 and Ras-GRF2. The Journal of Biological Chemistry. 289: 16551-64
Darcy MJ, Trouche S, Jin SX, et al. (2014) Age-dependent role for Ras-GRF1 in the late stages of adult neurogenesis in the dentate gyrus. Hippocampus. 24: 315-25
Jin SX, Arai J, Tian X, et al. (2013) Acquisition of contextual discrimination involves the appearance of a RAS-GRF1/p38 mitogen-activated protein (MAP) kinase-mediated signaling pathway that promotes long term potentiation (LTP). The Journal of Biological Chemistry. 288: 21703-13
Saavedra-Rodríguez L, Feig LA. (2013) Chronic social instability induces anxiety and defective social interactions across generations. Biological Psychiatry. 73: 44-53
Feig LA. (2011) Regulation of Neuronal Function by Ras-GRF Exchange Factors. Genes & Cancer. 2: 306-19
Alt-Holland A, Sowalsky AG, Szwec-Levin Y, et al. (2011) Suppression of E-cadherin function drives the early stages of Ras-induced squamous cell carcinoma through upregulation of FAK and Src. The Journal of Investigative Dermatology. 131: 2306-15
Sowalsky AG, Alt-Holland A, Shamis Y, et al. (2011) RalA function in dermal fibroblasts is required for the progression of squamous cell carcinoma of the skin. Cancer Research. 71: 758-67
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