Mark H. Ginsberg

Affiliations: 
Molecular Pathology University of California, San Diego, La Jolla, CA 
Area:
Cell Biology, Molecular Biology, Biochemistry
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"Mark Ginsberg"
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Children

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Jacob R. Haling grad student 2010 UCSD
Asoka Banno grad student 2011 UCSD
Joe W. Ramos post-doc (Cell Biology Tree)
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Publications

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Liao Z, Gingras AR, Lagarrigue F, et al. (2021) Optogenetic-based Localization of Talin to the Plasma Membrane Promotes Activation of β3 Integrins. The Journal of Biological Chemistry. 100675
Wen L, Marki A, Roy P, et al. (2020) Kindlin-3 recruitment to the plasma membrane precedes high affinity β2 integrin and neutrophil arrest from rolling. Blood
Lagarrigue F, Paul DS, Gingras AR, et al. (2020) Talin1 is the Principal Platelet Rap1 Effector of Integrin Activation. Blood
Gingras AR, Ginsberg MH. (2020) Signal Transduction: Physical Deformation of the Membrane Activates Integrins. Current Biology : Cb. 30: R397-R400
Wen L, Marki A, Roy P, et al. (2020) Recruitment of kindlin‐3 to plasma membrane through its PH domain precedes high affinity β 2 integrin activation and neutrophil arrest The Faseb Journal. 34: 1-1
Sun H, Fan Z, Gingras AR, et al. (2019) Frontline Science: A flexible kink in the transmembrane domain impairs β2 integrin extension and cell arrest from rolling. Journal of Leukocyte Biology
Gingras AR, Lagarrigue F, Cuevas MN, et al. (2019) Rap1 binding and a lipid-dependent helix in talin F1 domain promote integrin activation in tandem. The Journal of Cell Biology
Fan Z, Kiosses WB, Sun H, et al. (2019) High-Affinity Bent β-Integrin Molecules in Arresting Neutrophils Face Each Other through Binding to ICAMs In cis. Cell Reports. 26: 119-130.e5
Lopez-Ramirez MA, Pham A, Girard R, et al. (2018) Cerebral cavernous malformations form an anticoagulant vascular domain. Blood
Lagarrigue F, Gingras AR, Paul DS, et al. (2018) Rap1 binding to the talin 1 F0 domain makes a minimal contribution to murine platelet GPIIb-IIIa activation. Blood Advances. 2: 2358-2368
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