Brian San Francisco, Ph.D.

Affiliations: 
2013 Biology & Biomedical Sciences (Plant Biology) Washington University, Saint Louis, St. Louis, MO 
Area:
General Biology, Biochemistry, Molecular Biology
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"Brian San Francisco"
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Robert G. Kranz grad student 2013 Washington University
 (The System I and System III Holocytochrome c Synthases in Cytochrome c Biogenesis.)
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Publications

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Babbitt SE, San Francisco B, Mendez DL, et al. (2014) Mechanisms of mitochondrial holocytochrome c synthase and the key roles played by cysteines and histidine of the heme attachment site, Cys-XX-Cys-His. The Journal of Biological Chemistry. 289: 28795-807
Babbitt SE, San Francisco B, Bretsnyder EC, et al. (2014) Conserved residues of the human mitochondrial holocytochrome c synthase mediate interactions with heme. Biochemistry. 53: 5261-71
San Francisco B, Kranz RG. (2014) Interaction of holoCcmE with CcmF in heme trafficking and cytochrome c biosynthesis. Journal of Molecular Biology. 426: 570-85
San Francisco B, Sutherland MC, Kranz RG. (2014) The CcmFH complex is the system I holocytochrome c synthetase: engineering cytochrome c maturation independent of CcmABCDE. Molecular Microbiology. 91: 996-1008
San Francisco B, Bretsnyder EC, Kranz RG. (2013) Human mitochondrial holocytochrome c synthase's heme binding, maturation determinants, and complex formation with cytochrome c. Proceedings of the National Academy of Sciences of the United States of America. 110: E788-97
Richard-Fogal CL, San Francisco B, Frawley ER, et al. (2012) Thiol redox requirements and substrate specificities of recombinant cytochrome c assembly systems II and III. Biochimica Et Biophysica Acta. 1817: 911-9
San Francisco B, Bretsnyder EC, Rodgers KR, et al. (2011) Heme ligand identification and redox properties of the cytochrome c synthetase, CcmF. Biochemistry. 50: 10974-85
Richard-Fogal CL, Frawley ER, Bonner ER, et al. (2009) A conserved haem redox and trafficking pathway for cofactor attachment. The Embo Journal. 28: 2349-59
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