Ren Sheng, Ph.D.

2013 Chemistry University of Illinois at Chicago, Chicago, IL, United States 
Molecular Biology, General Chemistry
"Ren Sheng"
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Wonhwa Cho grad student 2013 University of Illinois, Chicago
 (Lipid binding of PDZ domain containing proteins and its crucial effect on cellular signaling.)
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Cho W, Yoon Y, Liu SL, et al. (2017) Fluorescence-Based In Situ Quantitative Imaging for Cellular Lipids. Methods in Enzymology. 583: 19-33
Liu SL, Sheng R, Jung JH, et al. (2016) Orthogonal lipid sensors identify transbilayer asymmetry of plasma membrane cholesterol. Nature Chemical Biology
Sheng R, Jung DJ, Silkov A, et al. (2016) Lipids regulate Lck activity through their interactions with the Lck SH2 domain. The Journal of Biological Chemistry
Park MJ, Sheng R, Silkov A, et al. (2016) SH2 Domains Serve as Lipid-Binding Modules for pTyr-Signaling Proteins. Molecular Cell
Komura N, Suzuki KG, Ando H, et al. (2016) Raft-based interactions of gangliosides with a GPI-anchored receptor. Nature Chemical Biology
Klionsky DJ, Abdelmohsen K, Abe A, et al. (2016) Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222
Liu SL, Sheng R, O'Connor MJ, et al. (2014) Simultaneous in situ quantification of two cellular lipid pools using orthogonal fluorescent sensors. Angewandte Chemie (International Ed. in English). 53: 14387-91
Sheng R, Kim H, Lee H, et al. (2014) Cholesterol selectively activates canonical Wnt signalling over non-canonical Wnt signalling. Nature Communications. 5: 4393
Tsukamoto K, Wales TE, Daniels K, et al. (2013) Noncanonical role of the PDZ4 domain of the adaptor protein PDZK1 in the regulation of the hepatic high density lipoprotein receptor scavenger receptor class B, type I (SR-BI). The Journal of Biological Chemistry. 288: 19845-60
Sheng R, Chen Y, Yung Gee H, et al. (2012) Cholesterol modulates cell signaling and protein networking by specifically interacting with PDZ domain-containing scaffold proteins. Nature Communications. 3: 1249
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