Steven O. Mansoorabadi, Ph.D.

Affiliations: 
2006 University of Wisconsin, Madison, Madison, WI 
Area:
Biochemistry, General Biophysics
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"Steven Mansoorabadi"
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Parents

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George H. Reed grad student 2006 UW Madison
 (Characterization of paramagnetic intermediates in enzymatic reactions.)
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Publications

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Pierce E, Mansoorabadi SO, Can M, et al. (2017) Properties of intermediates in the catalytic cycle of oxalate oxidoreductase and its suicide inactivation by pyruvate. Biochemistry
Ngo PD, Mansoorabadi SO, Frey PA. (2016) Serine Protease Catalysis: A Computational Study of Tetrahedral Intermediates and Inhibitory Adducts. The Journal of Physical Chemistry. B
Mansoorabadi SO, Wu M, Tao Z, et al. (2014) Conformational activation of poly(ADP-ribose) polymerase-1 upon DNA binding revealed by small-angle X-ray scattering. Biochemistry. 53: 1779-88
Kim HJ, McCarty RM, Ogasawara Y, et al. (2013) GenK-catalyzed C-6' methylation in the biosynthesis of gentamicin: isolation and characterization of a cobalamin-dependent radical SAM enzyme. Journal of the American Chemical Society. 135: 8093-6
Chang WC, Mansoorabadi SO, Liu HW. (2013) Reaction of HppE with substrate analogues: evidence for carbon-phosphorus bond cleavage by a carbocation rearrangement. Journal of the American Chemical Society. 135: 8153-6
Chang WC, Dey M, Liu P, et al. (2013) Mechanistic studies of an unprecedented enzyme-catalysed 1,2-phosphono-migration reaction. Nature. 496: 114-8
Huang H, Chang WC, Pai PJ, et al. (2012) Evidence for radical-mediated catalysis by HppE: a study using cyclopropyl and methylenecyclopropyl substrate analogues. Journal of the American Chemical Society. 134: 16171-4
Choi SH, Mansoorabadi SO, Liu YN, et al. (2012) Analysis of UDP-D-apiose/UDP-D-xylose synthase-catalyzed conversion of UDP-D-apiose phosphonate to UDP-D-xylose phosphonate: implications for a retroaldol-aldol mechanism. Journal of the American Chemical Society. 134: 13946-9
Reed GH, Ragsdale SW, Mansoorabadi SO. (2012) Radical reactions of thiamin pyrophosphate in 2-oxoacid oxidoreductases. Biochimica Et Biophysica Acta. 1824: 1291-8
Calveras J, Thibodeaux CJ, Mansoorabadi SO, et al. (2012) Stereochemical studies of the type II isopentenyl diphosphate-dimethylallyl diphosphate isomerase implicate the FMN coenzyme in substrate protonation. Chembiochem : a European Journal of Chemical Biology. 13: 42-6
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