Nicholas J. Veomett, Ph.D.

Affiliations: 
2014 Weill Cornell Medical College, New York, NY, United States 
Area:
Pharmacology, Oncology, Immunology
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David A. Scheinberg grad student 2014 Weill Cornell Medical College
 (Regulating the therapeutic efficacy of a TCR-like antibody to intracellular WT1 via FC engineering and target modulation.)
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Publications

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Dao T, Pankov D, Scott A, et al. (2015) Therapeutic bispecific T-cell engager antibody targeting the intracellular oncoprotein WT1. Nature Biotechnology
Veomett N, Dao T, Liu H, et al. (2014) Therapeutic efficacy of an Fc-enhanced TCR-like antibody to the intracellular WT1 oncoprotein. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 4036-46
Veomett N, Dao T, Scheinberg DA. (2013) Therapeutic antibodies to intracellular targets in cancer therapy. Expert Opinion On Biological Therapy. 13: 1485-8
Mallikaratchy P, Gardner J, Nordstrøm LU, et al. (2013) A self-assembling short oligonucleotide duplex suitable for pretargeting. Nucleic Acid Therapeutics. 23: 289-99
Dao T, Yan S, Veomett N, et al. (2013) Targeting the intracellular WT1 oncogene product with a therapeutic human antibody. Science Translational Medicine. 5: 176ra33
Dubrovsky L, Brea EJ, Veomett NJ, et al. (2013) Therapeutic superiority of a TCR-like antibody to an intracellular WT1 oncogene peptide compared with the tyrosine kinase inhibitor imatinib in a mouse model of Philadelphia chromosome positive (Ph+) ALL. Journal of Clinical Oncology. 31: 3047-3047
Dubrovsky L, Brea E, Pankov D, et al. (2013) Therapeutic Efficacy and Cure Of Sensitive and T315I Pan-Resistant Human Ph+ Leukemia In Mice Using a TCR-Like Antibody To WT1/HLA-A0201 Alone, Or In Combination With Tyrosine Kinase Inhibitors Blood. 122: 855-855
Pankov D, Dao T, Wang Y, et al. (2013) A Bi-Specific T Cell Engaging Monoclonal Antibody (mAb) Derived From a TCR-Like Mab Specific For WT1/HLA-A0201 (ESK-BiTE) Shows a Potent Activity Against Human AML and Ph+ ALL In Mouse Models Blood. 122: 2521-2521
Tseng HM, Shum D, Bhinder B, et al. (2012) A high-throughput scintillation proximity-based assay for human DNA ligase IV. Assay and Drug Development Technologies. 10: 235-49
Veomett N, Dao T, Pankov D, et al. (2012) Native and Fc Enhanced Therapeutic Human Monoclonal Antibodies Targeting the Intracellular WT1 Oncogene Product in Leukemia. Blood. 120: 2599-2599
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