Truc C. Pham, Ph.D.

Affiliations: 
2005 The University of Memphis, Memphis, TN, United States 
Area:
Biochemistry
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"Truc Pham"
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Abby L. Parrill grad student 2005 The University of Memphis
 (Structural studies of sphingosine 1 -phosphate receptors.)
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Publications

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Banerjee S, Norman DD, Lee SC, et al. (2017) Highly Potent Non-Carboxylic Acid Autotaxin Inhibitors Reduce Melanoma Metastasis and Chemotherapeutic Resistance of Breast Cancer Stem Cells. Journal of Medicinal Chemistry
Fells JI, Lee SC, Norman DD, et al. (2014) Targeting the hydrophobic pocket of autotaxin with virtual screening of inhibitors identifies a common aromatic sulfonamide structural motif. The Febs Journal. 281: 1017-28
Young JK, Clayton BT, Kikonyogo A, et al. (2013) Structural Characterization of an LPA1 Second Extracellular Loop Mimetic with a Self-Assembling Coiled-Coil Folding Constraint. International Journal of Molecular Sciences. 14: 2788-807
Parrill AL, Wanjala IW, Pham TC, et al. (2011) Computational identification and experimental characterization of substrate binding determinants of nucleotide pyrophosphatase/phosphodiesterase 7. Bmc Biochemistry. 12: 65
Gupte R, Patil R, Liu J, et al. (2011) Benzyl and naphthalene methylphosphonic acid inhibitors of autotaxin with anti-invasive and anti-metastatic activity. Chemmedchem. 6: 922-35
Gupte R, Siddam A, Lu Y, et al. (2010) Synthesis and pharmacological evaluation of the stereoisomers of 3-carba cyclic-phosphatidic acid. Bioorganic & Medicinal Chemistry Letters. 20: 7525-8
Valentine WJ, Kiss GN, Liu J, et al. (2010) (S)-FTY720-vinylphosphonate, an analogue of the immunosuppressive agent FTY720, is a pan-antagonist of sphingosine 1-phosphate GPCR signaling and inhibits autotaxin activity. Cellular Signalling. 22: 1543-53
North EJ, Howard AL, Wanjala IW, et al. (2010) Pharmacophore development and application toward the identification of novel, small-molecule autotaxin inhibitors. Journal of Medicinal Chemistry. 53: 3095-105
Hoeglund AB, Howard AL, Wanjala IW, et al. (2010) Characterization of non-lipid autotaxin inhibitors. Bioorganic & Medicinal Chemistry. 18: 769-76
Pham TC, Fells JI, Osborne DA, et al. (2008) Molecular recognition in the sphingosine 1-phosphate receptor family. Journal of Molecular Graphics & Modelling. 26: 1189-201
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