Truc C. Pham, Ph.D.
Affiliations: | 2005 | The University of Memphis, Memphis, TN, United States |
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Parents
Sign in to add mentorAbby L. Parrill | grad student | 2005 | The University of Memphis | |
(Structural studies of sphingosine 1 -phosphate receptors.) |
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Publications
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Banerjee S, Norman DD, Lee SC, et al. (2017) Highly Potent Non-Carboxylic Acid Autotaxin Inhibitors Reduce Melanoma Metastasis and Chemotherapeutic Resistance of Breast Cancer Stem Cells. Journal of Medicinal Chemistry |
Fells JI, Lee SC, Norman DD, et al. (2014) Targeting the hydrophobic pocket of autotaxin with virtual screening of inhibitors identifies a common aromatic sulfonamide structural motif. The Febs Journal. 281: 1017-28 |
Young JK, Clayton BT, Kikonyogo A, et al. (2013) Structural Characterization of an LPA1 Second Extracellular Loop Mimetic with a Self-Assembling Coiled-Coil Folding Constraint. International Journal of Molecular Sciences. 14: 2788-807 |
Parrill AL, Wanjala IW, Pham TC, et al. (2011) Computational identification and experimental characterization of substrate binding determinants of nucleotide pyrophosphatase/phosphodiesterase 7. Bmc Biochemistry. 12: 65 |
Gupte R, Patil R, Liu J, et al. (2011) Benzyl and naphthalene methylphosphonic acid inhibitors of autotaxin with anti-invasive and anti-metastatic activity. Chemmedchem. 6: 922-35 |
Gupte R, Siddam A, Lu Y, et al. (2010) Synthesis and pharmacological evaluation of the stereoisomers of 3-carba cyclic-phosphatidic acid. Bioorganic & Medicinal Chemistry Letters. 20: 7525-8 |
Valentine WJ, Kiss GN, Liu J, et al. (2010) (S)-FTY720-vinylphosphonate, an analogue of the immunosuppressive agent FTY720, is a pan-antagonist of sphingosine 1-phosphate GPCR signaling and inhibits autotaxin activity. Cellular Signalling. 22: 1543-53 |
North EJ, Howard AL, Wanjala IW, et al. (2010) Pharmacophore development and application toward the identification of novel, small-molecule autotaxin inhibitors. Journal of Medicinal Chemistry. 53: 3095-105 |
Hoeglund AB, Howard AL, Wanjala IW, et al. (2010) Characterization of non-lipid autotaxin inhibitors. Bioorganic & Medicinal Chemistry. 18: 769-76 |
Pham TC, Fells JI, Osborne DA, et al. (2008) Molecular recognition in the sphingosine 1-phosphate receptor family. Journal of Molecular Graphics & Modelling. 26: 1189-201 |