Gordon S. Rule
Affiliations: | 1996 | Biochemistry | University of Virginia School of Medicine, Charlottesville, VA, United States |
| 1996- | Carnegie Mellon University, Pittsburgh, PA |
Area:
General Biophysics, BiochemistryWebsite:
https://www.cmu.edu/bio/people/faculty/rule.htmlGoogle:
"Gordon Steven Rule" OR "Gordon S Rule"Bio:
https://www.hbku.edu.qa/en/staff/gordon-s-rule
https://books.google.com/books?id=p50vAQAAIAAJ
https://books.google.com/books?id=IldEAQAAIAAJ
Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Reginald A. Deering | grad student | 1981 | Penn State | |
| (M.S. thesis: Electrophoretic Characterization of Non-specific Endodeoxyribonucleases from Dictyostelium discoideum.) | ||||
| Chien Ho | grad student | 1986 | Carnegie Mellon | |
| (Biochemical, biophysical, and molecular genetic studies on the membrane-bound D-lactate dehydrogenase from Escherichia coli) | ||||
| Harden M. McConnell | post-doc | 1988 | Stanford | |
Children
Sign in to add trainee| Yiping Zhan | grad student | 2004 | Carnegie Mellon |
| Kaustubh Sinha | grad student | 2009 | Carnegie Mellon |
| Shantanu S. Bhattacharyya | grad student | 2013 | Carnegie Mellon |
| Andrew D Kehr | grad student | 2009-2015 | Carnegie Mellon |
| Ian Fucci | grad student | 2014-2019 | Carnegie Mellon |
Collaborators
Sign in to add collaborator| Robert M. Straubinger | collaborator | 1981 | Carnegie Mellon (BME Tree) |
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Publications
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| Fucci IJ, Sinha K, Rule GS. (2021) Protein Dynamics Is Altered by a High Surface Density of Atomic Transfer Radical Polymerization Polymers. Langmuir : the Acs Journal of Surfaces and Colloids |
| Sinha K, Rule GS. (2021) Conformational Diversity Defines Substrate Specificity of Thymidylate/Uridylate Kinase from Candida albicans. Proteins |
| Singewald K, Bogetti X, Sinha K, et al. (2020) Double Histidine based EPR measurements at physiological temperatures permit site-specific elucidation of hidden dynamics in enzymes. Angewandte Chemie (International Ed. in English) |
| Fucci IJ, Sinha K, Rule GS. (2020) Stabilization of Active Site Dynamics Leads to Increased Activity with 3'-Azido-3'-deoxythymidine Monophosphate for F105Y Mutant Human Thymidylate Kinase. Acs Omega. 5: 2355-2367 |
| Chen MD, Fucci IJ, Sinha K, et al. (2020) dGMP Binding to Thymidylate Kinase from Shows Half-Site Binding and Induces Protein Dynamics at the Dimer Interface. Biochemistry |
| Chen M, Sinha K, Rule GS, et al. (2018) Interaction of α-Thymidine Inhibitors with Thymidylate Kinase from Plasmodium falciparum. Biochemistry |
| Thadke S, Perera JDR, Hridya VM, et al. (2018) Design of Bivalent Nucleic Acid Ligands for Recognition of RNA-Repeated Expansion Associated with Huntington's Disease. Biochemistry |
| Lawless MJ, Pettersson JR, Rule GS, et al. (2018) ESR Resolves the C Terminus Structure of the Ligand-free Human Glutathione S-Transferase A1-1. Biophysical Journal. 114: 592-601 |
| Sinha K, Sangani S, Rule G, et al. (2018) Backbone assignments and ILV methyl assignments for EcoRV bound to 16-mer double stranded DNA (GCAAAGATATCTTTCG) without Lu3+ Journal of Back and Musculoskeletal Rehabilitation |
| Ghosh S, Lawless MJ, Rule GS, et al. (2017) The Cu2+-nitrilotriacetic acid complex improves loading of α-helical double histidine site for precise distance measurements by pulsed ESR. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 286: 163-171 |