Lucio Miele

Molecular and Cellular Biochemistry Program Loyola University Chicago, Chicago, IL, United States 
Molecular Biology, Oncology
"Lucio Miele"
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Monticone G, Huang Z, Csibi F, et al. (2022) Targeting the Cbl-b-Notch1 axis as a novel immunotherapeutic strategy to boost CD8+ T-cell responses. Frontiers in Immunology. 13: 987298
Perrone C, Pomella S, Cassandri M, et al. (2022) MET Inhibition Sensitizes Rhabdomyosarcoma Cells to NOTCH Signaling Suppression. Frontiers in Oncology. 12: 835642
Hoang VT, Matossian MD, La J, et al. (2021) Dual inhibition of MEK1/2 and MEK5 suppresses the EMT/migration axis in triple-negative breast cancer through FRA-1 regulation. Journal of Cellular Biochemistry
Bhatt AB, Wright TD, Barnes V, et al. (2021) Diverse and converging roles of ERK1/2 and ERK5 pathways on mesenchymal to epithelial transition in breast cancer. Translational Oncology. 14: 101046
Bhatt AB, Patel S, Matossian MD, et al. (2021) Molecular Mechanisms of Epithelial to Mesenchymal Transition Regulated by ERK5 Signaling. Biomolecules. 11
Monticone G, Miele L. (2021) Notch Pathway: A Journey from Notching Phenotypes to Cancer Immunotherapy. Advances in Experimental Medicine and Biology. 1287: 201-222
Majumder S, Crabtree JS, Golde TE, et al. (2020) Targeting Notch in oncology: the path forward. Nature Reviews. Drug Discovery
Chang TC, Matossian MD, Elliott S, et al. (2020) Evaluation of deacetylase inhibition in metaplastic breast carcinoma using multiple derivations of preclinical models of a new patient-derived tumor. Plos One. 15: e0226464
Hoang VT, Matossian MD, Ucar DA, et al. (2020) ERK5 Is Required for Tumor Growth and Maintenance Through Regulation of the Extracellular Matrix in Triple Negative Breast Cancer. Frontiers in Oncology. 10: 1164
Matossian MD, Burks HE, Elliott S, et al. (2020) A novel screening approach comparing kinase activity of small molecule inhibitors with similar molecular structures and distinct biologic effects in triple-negative breast cancer to identify targetable signaling pathways. Anti-Cancer Drugs. 31: 759-775
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