Wayne W. Harding

Affiliations: 
Chemistry City University of New York, New York, NY, United States 
Area:
Organic Chemistry
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"Wayne Harding"
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Onica Le Gendre grad student 2010 CUNY
Stevan Pecic grad student 2010 CUNY
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Karki A, Namballa HK, Alberts I, et al. (2020) Structural manipulation of aporphines via C10 nitrogenation leads to the identification of new 5-HTR ligands. Bioorganic & Medicinal Chemistry. 28: 115578
Giri R, Namballa HK, Sarker A, et al. (2020) Synthesis and dopamine receptor pharmacological evaluations on ring C ortho halogenated 1-phenylbenzazepines. Bioorganic & Medicinal Chemistry Letters. 30: 127305
Giri R, Alberts I, Harding WW. (2020) Synthesis, pharmacological evaluations, and molecular docking studies on a new 1,3,4,11b-tetrahydro-1H-fluoreno[9,1-cd]azepine framework: Rigidification of D receptor selective 1-phenylbenzazepines and discovery of a new 5-HT receptor scaffold. Chemical Biology & Drug Design
Karki A, Juarez R, Namballa HK, et al. (2020) Identification of C10 nitrogen-containing aporphines with dopamine D versus D receptor selectivity. Bioorganic & Medicinal Chemistry Letters. 127053
Cordone P, Namballa HK, Harding WW. (2020) First synthesis of thiazepino[3,4‐a]isoquinolines, a facile new synthetic route to diazepino[3,4‐a]isoquinolines and assessment of their dopamine and σ receptor affinities Journal of Heterocyclic Chemistry
Pal RK, Gadhiya S, Ramsey S, et al. (2019) Inclusion of enclosed hydration effects in the binding free energy estimation of dopamine D3 receptor complexes. Plos One. 14: e0222902
Gadhiya S, Cordone P, Pal RK, et al. (2018) New Dopamine D3-Selective Receptor Ligands Containing a 6-Methoxy-1,2,3,4-tetrahydroisoquinolin-7-ol Motif. Acs Medicinal Chemistry Letters. 9: 990-995
Marchant JS, Harding WW, Chan JD. (2018) Structure-activity profiling of alkaloid natural product pharmacophores against a Schistosoma serotonin receptor. International Journal For Parasitology. Drugs and Drug Resistance
Madapa S, Gadhiya S, Kurtzman T, et al. (2016) Synthesis and evaluation of C9 alkoxy analogues of (-)-stepholidine as dopamine receptor ligands. European Journal of Medicinal Chemistry. 125: 255-268
Kapadia N, Ahmed S, Harding WW. (2016) New halogenated tris-(phenylalkyl)amines as h5-HT2B receptor ligands. Bioorganic & Medicinal Chemistry Letters
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