Alejandro Chavez, Ph.D.

Affiliations: 
2010 University of Pennsylvania, Philadelphia, PA, United States 
Area:
Molecular Biology, Genetics, Biochemistry
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"Alejandro Chavez"
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Parents

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Frederich B. Johnson grad student 2010 Penn
 (Novel roles for the SMC5/6 complex and DNA helicase MPH1 in template switch recombination.)
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Publications

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Lampe GD, King RT, Halpin-Healy TS, et al. (2023) Targeted DNA integration in human cells without double-strand breaks using CRISPR RNA-guided transposases. Biorxiv : the Preprint Server For Biology
Lampe GD, King RT, Halpin-Healy TS, et al. (2023) Targeted DNA integration in human cells without double-strand breaks using CRISPR-associated transposases. Nature Biotechnology
Moghadam F, LeGraw R, Velazquez JJ, et al. (2020) Synthetic immunomodulation with a CRISPR super-repressor in vivo. Nature Cell Biology. 22: 1143-1154
Halder V, Porter CBM, Chavez A, et al. (2019) Author Correction: Design, execution, and analysis of CRISPR-Cas9-based deletions and genetic interaction networks in the fungal pathogen Candida albicans. Nature Protocols
Xiong K, Marquart KF, Karottki KJC, et al. (2019) Reduced Apoptosis in Chinese Hamster Ovary Cells via Optimized CRISPR Interference. Biotechnology and Bioengineering
Labun K, Guo X, Chavez A, et al. (2019) Accurate analysis of genuine CRISPR editing events with ampliCan. Genome Research
Halder V, Porter CBM, Chavez A, et al. (2019) Design, execution, and analysis of CRISPR-Cas9-based deletions and genetic interaction networks in the fungal pathogen Candida albicans. Nature Protocols
Yeo NC, Chavez A, Lance-Byrne A, et al. (2018) An enhanced CRISPR repressor for targeted mammalian gene regulation. Nature Methods
Clarke R, Heler R, MacDougall MS, et al. (2018) Enhanced Bacterial Immunity and Mammalian Genome Editing via RNA-Polymerase-Mediated Dislodging of Cas9 from Double-Strand DNA Breaks. Molecular Cell. 71: 42-55.e8
Guo X, Chavez A, Tung A, et al. (2018) High-throughput creation and functional profiling of DNA sequence variant libraries using CRISPR-Cas9 in yeast. Nature Biotechnology
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