Jane X. Kelly, Ph.D.

Affiliations: 
2003 Portland State University, Portland, OR, United States 
Area:
Biochemistry, Pharmaceutical Chemistry
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David H. Peyton grad student 2003 Portland State University
 (Investigation of the 3,6-bis-o-diethylaminoalkoxyxanthone series as antimalarial and antileishmanial agents.)
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Publications

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Smilkstein MJ, Pou S, Krollenbrock A, et al. (2019) ELQ-331 as a prototype for extremely durable chemoprotection against malaria. Malaria Journal. 18: 291
Dodean RA, Kancharla P, Li Y, et al. (2019) Discovery and Structural Optimization of Acridones as Broad-Spectrum Antimalarials. Journal of Medicinal Chemistry
Frueh L, Li Y, Mather M, et al. (2017) Alkoxycarbonate Ester Prodrugs of Preclinical Drug Candidate ELQ-300 for Prophylaxis and Treatment of Malaria. Acs Infectious Diseases
Gunsaru B, Burgess SJ, Morrill W, et al. (2017) Simplified Reversed Chloroquines to Overcome Malaria Resistance to Quinoline-based Drugs. Antimicrobial Agents and Chemotherapy
Foss MH, Pou S, Davidson PM, et al. (2016) Diphenylether-Modified 1,2-Diamines with Improved Drug Properties for Development against Mycobacterium tuberculosis. Acs Infectious Diseases. 2: 500-508
Abugrain ME, Lu W, Li Y, et al. (2016) Interrogating the Tailoring Steps of Pactamycin Biosynthesis and Accessing New Pactamycin Analogues. Chembiochem : a European Journal of Chemical Biology
Stickles AM, Smilkstein MJ, Morrisey JM, et al. (2016) Atovaquone and ELQ-300 combination therapy: A novel dual-site cytochrome bc1 inhibition strategy for malaria. Antimicrobial Agents and Chemotherapy
Abugrain ME, Lu W, Li Y, et al. (2016) Cover Picture: Interrogating the Tailoring Steps of Pactamycin Biosynthesis and Accessing New Pactamycin Analogues (ChemBioChem 17/2016) Chembiochem. 17: 1579
Kancharla P, Kelly JX, Reynolds KA. (2015) Synthesis and Structure-Activity Relationships of Tambjamines and B-Ring Functionalized Prodiginines as Potent Antimalarials. Journal of Medicinal Chemistry. 58: 7286-309
Miley GP, Pou S, Winter R, et al. (2015) ELQ-300 prodrugs for enhanced delivery and single dose cure of malaria. Antimicrobial Agents and Chemotherapy
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