Ravindra A. De Silva, Ph.D.

Affiliations: 
2009 Chemistry Wayne State University, Detroit, MI, United States 
Area:
Organic Chemistry
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Peter R. Andreana grad student 2009 Wayne State
 (I. Immunological response from an entirely carbohydrate antigen: Design and synthesis of a cancer vaccine candidate based on Tn-PS A1 conjugate II. Microwave assisted one-pot two step synthesis of 1,2,4,5-tetrahydro-1,4-benzodiazepin-3-ones for cancer the)
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Publications

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Trabbic KR, De Silva RA, Andreana PR. (2014) Elucidating Structural Features of an Entirely Carbohydrate Cancer Vaccine Construct Employing Circular Dichroism and Fluorescent Labeling. Medchemcomm. 5: 1143-1149
Woodard LE, De Silva RA, Behnam Azad B, et al. (2014) Bridged cyclams as imaging agents for chemokine receptor 4 (CXCR4). Nuclear Medicine and Biology. 41: 552-61
Chang AJ, De Silva RA, Lapi SE. (2013) Development and characterization of 89Zr-labeled panitumumab for immuno-positron emission tomographic imaging of the epidermal growth factor receptor. Molecular Imaging. 12: 17-27
Chang AJ, De Silva RA, Lapi SE. (2013) Development and characterization of 89Zr-labeled panitumumab for immuno-positron emission tomographic imaging of the epidermal growth factor receptor Molecular Imaging. 12: 1-11
De Silva RA, Jain S, Lears KA, et al. (2012) Copper-64 radiolabeling and biological evaluation of bifunctional chelators for radiopharmaceutical development. Nuclear Medicine and Biology. 39: 1099-104
De Silva RA, Appulage DK, Pietraszkiewicz H, et al. (2012) The entirely carbohydrate immunogen Tn-PS A1 induces a cancer cell selective immune response and cytokine IL-17. Cancer Immunology, Immunotherapy : Cii. 61: 581-5
Craft JM, De Silva RA, Lears KA, et al. (2012) In vitro and in vivo evaluation of a 64Cu-labeled NOTA-Bn-SCN-Aoc-bombesin analogue in gastrin-releasing peptide receptor expressing prostate cancer. Nuclear Medicine and Biology. 39: 609-16
De Silva RA, Peyre K, Pullambhatla M, et al. (2011) Imaging CXCR4 expression in human cancer xenografts: evaluation of monocyclam 64Cu-AMD3465. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 52: 986-93
De Silva RA, Wang Q, Chidley T, et al. (2009) Immunological response from an entirely carbohydrate antigen: design of synthetic vaccines based on Tn-PS A1 conjugates. Journal of the American Chemical Society. 131: 9622-3
De Silva RA, Santra S, Andreana PR. (2008) A tandem one-pot, microwave-assisted synthesis of regiochemically differentiated 1,2,4,5-tetrahydro-1,4-benzodiazepin-3-ones. Organic Letters. 10: 4541-4
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