Pankaj K. Singh, Ph.D.

Affiliations: 
2007 University of Nebraska Medical Center, Omaha, NE, United States 
Area:
Biochemistry, Oncology, Molecular Biology
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"Pankaj Singh"
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Michael A. Hollingsworth grad student 2007 University of Nebraska Medical Center
 (Phosphorylation-mediated signaling of MUC1 cytoplasmic tail in pancreatic cancer.)
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Publications

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Mullen NJ, Shukla SK, Thakur R, et al. (2024) DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation. Elife. 12
Murthy D, Attri KS, Shukla SK, et al. (2024) Author Correction: Cancer-associated fibroblast-derived acetate promotes pancreatic cancer development by altering polyamine metabolism via the ACSS2-SP1-SAT1 axis. Nature Cell Biology
Murthy D, Attri KS, Suresh V, et al. (2024) The MUC1-HIF-1α signaling axis regulates pancreatic cancer pathogenesis through polyamine metabolism remodeling. Proceedings of the National Academy of Sciences of the United States of America. 121: e2315509121
Treekitkarnmongkol W, Solis LM, Sankaran D, et al. (2024) eEF1A2 promotes PTEN-GSK3β-SCF complex-dependent degradation of Aurora kinase A and is inactivated in breast cancer. Science Signaling. 17: eadh4475
Murthy D, Attri KS, Shukla SK, et al. (2024) Cancer-associated fibroblast-derived acetate promotes pancreatic cancer development by altering polyamine metabolism via the ACSS2-SP1-SAT1 axis. Nature Cell Biology
Chumak V, Rajacharya GH, Singh PK. (2024) Metabolomic Investigations into Hypoxia-Mediated Metabolic Reprogramming of Pancreatic Cancer Cells. Methods in Molecular Biology (Clifton, N.J.). 2755: 191-200
Singh PK, Mehla K. (2023) LXR Signaling-Mediated Cholesterol Metabolism Reprogramming Regulates Cancer Cell Metastasis. Cancer Research. 83: 1759-1761
Mullen NJ, Shukla SK, Thakur R, et al. (2023) DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation. Biorxiv : the Preprint Server For Biology
Mullen NJ, Singh PK. (2023) Nucleotide metabolism: a pan-cancer metabolic dependency. Nature Reviews. Cancer. 23: 275-294
Mullen NJ, Thakur R, Shukla SK, et al. (2022) ENT1 blockade by CNX-774 overcomes resistance to DHODH inhibition in pancreatic cancer. Cancer Letters. 552: 215981
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