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Liqiang Chen, Ph.D.

Affiliations: 
2002 University of Iowa, Iowa City, IA 
Area:
Organic Chemistry
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"Liqiang Chen"
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David F. Wiemer grad student 2002 University of Iowa
 (Synthesis of mannosamine derivatives and analogs.)

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Publications

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Ding R, Zhang T, Wilson DJ, et al. (2019) Discovery of Irreversible p97 Inhibitors. Journal of Medicinal Chemistry
Ding R, Zhang T, Xie J, et al. (2016) Eeyarestatin I derivatives with improved aqueous solubility. Bioorganic & Medicinal Chemistry Letters
Ai T, Wilson DJ, More SS, et al. (2016) 5-((3-Amidobenzyl)oxy)nicotinamides as Sirtuin 2 Inhibitors. Journal of Medicinal Chemistry
Ai T, Qiu L, Xie J, et al. (2015) Design and synthesis of an activity-based protein profiling probe derived from cinnamic hydroxamic acid. Bioorganic & Medicinal Chemistry
Cui H, Kamal Z, Ai T, et al. (2014) Discovery of potent and selective sirtuin 2 (SIRT2) inhibitors using a fragment-based approach. Journal of Medicinal Chemistry. 57: 8340-57
Ai T, Cui H, Chen L. (2012) Multi-Targeted Histone Deacetylase Inhibitors in Cancer Therapy Current Medicinal Chemistry. 19: 475-487
Chen L. (2011) Medicinal chemistry of sirtuin inhibitors. Current Medicinal Chemistry. 18: 1936-1946
Felczak K, Chen L, Wilson D, et al. (2011) Cofactor-type inhibitors of inosine monophosphate dehydrogenase via modular approach: targeting the pyrophosphate binding sub-domain. Bioorganic & Medicinal Chemistry. 19: 1594-605
Chen L, Petrelli R, Gao G, et al. (2010) Dual inhibitors of inosine monophosphate dehydrogenase and histone deacetylase based on a cinnamic hydroxamic acid core structure. Bioorganic & Medicinal Chemistry. 18: 5950-64
Chen L, Wilson DJ, Xu Y, et al. (2010) Triazole-linked inhibitors of inosine monophosphate dehydrogenase from human and Mycobacterium tuberculosis. Journal of Medicinal Chemistry. 53: 4768-78
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