Liqiang Chen, Ph.D.

Affiliations: 
2002 University of Iowa, Iowa City, IA 
Area:
Organic Chemistry
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"Liqiang Chen"
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David F. Wiemer grad student 2002 University of Iowa
 (Synthesis of mannosamine derivatives and analogs.)
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Publications

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Vogel RI, Pulver T, Heilmann W, et al. (2016) USP14 is a predictor of recurrence in endometrial cancer and a molecular target for endometrial cancer treatment. Oncotarget
Ai T, Wilson DJ, More SS, et al. (2016) 5-((3-Amidobenzyl)oxy)nicotinamides as Sirtuin 2 Inhibitors. Journal of Medicinal Chemistry
Alhazzazi TY, Kamarajan P, Xu Y, et al. (2016) A Novel Sirtuin-3 Inhibitor, LC-0296, Inhibits Cell Survival and Proliferation, and Promotes Apoptosis of Head and Neck Cancer Cells. Anticancer Research. 36: 49-60
Ai T, Qiu L, Xie J, et al. (2015) Design and synthesis of an activity-based protein profiling probe derived from cinnamic hydroxamic acid. Bioorganic & Medicinal Chemistry
Ai T, Xu Y, Qiu L, et al. (2015) Hydroxamic acids block replication of hepatitis C virus. Journal of Medicinal Chemistry. 58: 785-800
Cui H, Kamal Z, Ai T, et al. (2014) Discovery of potent and selective sirtuin 2 (SIRT2) inhibitors using a fragment-based approach. Journal of Medicinal Chemistry. 57: 8340-57
Felczak K, Chen L, Wilson D, et al. (2011) Cofactor-type inhibitors of inosine monophosphate dehydrogenase via modular approach: targeting the pyrophosphate binding sub-domain. Bioorganic & Medicinal Chemistry. 19: 1594-605
Chen L, Petrelli R, Gao G, et al. (2010) Dual inhibitors of inosine monophosphate dehydrogenase and histone deacetylase based on a cinnamic hydroxamic acid core structure. Bioorganic & Medicinal Chemistry. 18: 5950-64
Chen L, Wilson DJ, Xu Y, et al. (2010) Triazole-linked inhibitors of inosine monophosphate dehydrogenase from human and Mycobacterium tuberculosis. Journal of Medicinal Chemistry. 53: 4768-78
Petrelli R, Sham YY, Chen L, et al. (2009) Selective inhibition of nicotinamide adenine dinucleotide kinases by dinucleoside disulfide mimics of nicotinamide adenine dinucleotide analogues. Bioorganic & Medicinal Chemistry. 17: 5656-64
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