Stewart Shuman
Affiliations: | Weill Cornell Medical College, New York, NY, United States |
Area:
Molecular Biology, BiochemistryGoogle:
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Children
Sign in to add traineeKevin Lehman | grad student | 2001 | Weill Cornell Medical College |
Chunling Gong | grad student | 2004 | Weill Cornell Medical College |
Rana Sawaya | grad student | 2004 | Weill Cornell Medical College |
Ligeng Tian | grad student | 2005 | Weill Cornell Medical College |
Niroshika Keppetipola | grad student | 2009 | Weill Cornell Medical College |
Ruchi Jain | grad student | 2010 | Weill Cornell Medical College |
Zhicheng Qiu | grad student | 2012 | Weill Cornell Medical College |
Poulami Samai | grad student | 2012 | Weill Cornell Medical College |
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Publications
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Ghosh S, Wimberly-Gard G, Jacewicz A, et al. (2024) Identification, characterization, and structure of a tRNA splicing enzyme RNA 5'-OH kinase from the pathogenic fungi Mucorales. Rna (New York, N.Y.) |
Arnold J, Ghosh S, Kasprzyk R, et al. (2024) Chemical synthesis of 2″OMeNAD+ and its deployment as an RNA 2'-phosphotransferase (Tpt1) 'poison' that traps the enzyme on its abortive RNA-2'-PO4-(ADP-2″OMe-ribose) reaction intermediate. Nucleic Acids Research |
Ghosh S, Shuman S. (2024) Kinetic and structural insights into the requirement of fungal tRNA ligase for a 2'-phosphate end. Rna (New York, N.Y.) |
Warren GM, Shuman S. (2024) Structure and psoralen DNA crosslink repair activity of mycobacterial Nei2. Mbio. e0124824 |
Schwer B, Innokentev A, Sanchez AM, et al. (2024) Suppression of inositol pyrophosphate toxicosis and hyper-repression of the fission yeast regulon by loss-of-function mutations in chromatin remodelers Snf22 and Sol1. Mbio. e0125224 |
Ghosh S, Dantuluri S, Jacewicz A, et al. (2024) Characterization of tRNA splicing enzymes RNA ligase and tRNA 2'-phosphotransferase from the pathogenic fungi . Rna (New York, N.Y.) |
Jacewicz A, Dantuluri S, Shuman S. (2023) Structural basis for Tpt1-catalyzed 2'-PO transfer from RNA and NADP(H) to NAD. Proceedings of the National Academy of Sciences of the United States of America. 120: e2312999120 |
Sanchez AM, Schwer B, Jork N, et al. (2023) Activities, substrate specificity, and genetic interactions of fission yeast Siw14, a cysteinyl-phosphatase-type inositol pyrophosphatase. Mbio. e0205623 |
Shuman S. (2023) RNA Repair: Hiding in Plain Sight. Annual Review of Genetics |
Garg A, Schwer B, Shuman S. (2023) Fission yeast poly(A) polymerase active site mutation Y86D alleviates the synthetic growth defect and upregulates mRNAs targeted by MTREC and Mmi1. Rna (New York, N.Y.) |