Joseph J. Barycki

Affiliations: 
2002-2017 Biochemistry The University of Nebraska - Lincoln, Lincoln, NE 
 2017- Molecular and Structural Biochemistry North Carolina State University, Raleigh, NC 
Area:
glutathione, UDP-glucose dehydrogenase, structure/function
Website:
https://cals.ncsu.edu/molecular-and-structural-biochemistry/people/joe-barycki/
Google:
"Joseph J. Barycki"
Bio:

https://barycki.wordpress.ncsu.edu/

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Publications

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Grady G, Thelen AM, Albers J, et al. (2016) Inhibiting hexamer disassembly of UDP-glucose dehydrogenase by photoactivated amino acid crosslinking. Biochemistry
Palmer M, Ma L, Romsdahl T, et al. (2016) Abstract C41: Altered control of intracellular androgen availability by glucuronidation contributes to loss of androgen dependence in prostate tumor cells Cancer Research. 76
Ozer HK, Dlouhy AC, Thornton JD, et al. (2015) Cytosolic Fe-S Cluster Protein Maturation and Iron Regulation Are Independent of the Mitochondrial Erv1/Mia40 Import System. The Journal of Biological Chemistry
McAtee CO, Berkebile AR, Elowsky CG, et al. (2015) Hyaluronidase Hyal1 Increases Tumor Cell Proliferation and Motility through Accelerated Vesicle Trafficking. The Journal of Biological Chemistry. 290: 13144-56
McAtee CO, Barycki JJ, Simpson MA. (2014) Emerging roles for hyaluronidase in cancer metastasis and therapy. Advances in Cancer Research. 123: 1-34
Liu Y, Hyde AS, Simpson MA, et al. (2014) Emerging regulatory paradigms in glutathione metabolism. Advances in Cancer Research. 122: 69-101
Hyde AS, Thelen AM, Barycki JJ, et al. (2013) UDP-glucose dehydrogenase activity and optimal downstream cellular function require dynamic reorganization at the dimer-dimer subunit interfaces Journal of Biological Chemistry. 288: 35049-35057
Hyde AS, Farmer EL, Easley KE, et al. (2012) UDP-glucose dehydrogenase polymorphisms from patients with congenital heart valve defects disrupt enzyme stability and quaternary assembly. The Journal of Biological Chemistry. 287: 32708-16
Willis MN, Liu Y, Biterova EI, et al. (2011) Enzymatic defects underlying hereditary glutamate cysteine ligase deficiency are mitigated by association of the catalytic and regulatory subunits. Biochemistry. 50: 6508-17
Biterova EI, Barycki JJ. (2010) Structural basis for feedback and pharmacological inhibition of Saccharomyces cerevisiae glutamate cysteine ligase. The Journal of Biological Chemistry. 285: 14459-66
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