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Erkang Fan

Affiliations: 
University of Washington, Seattle, Seattle, WA 
Area:
Biochemistry
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"Erkang Fan"
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Parents

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Andrew D. Hamilton grad student 1988-1993 University of Pittsburgh
Peter G. Schultz post-doc 1993-1996 UC Berkeley

Children

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Jiyun Liu grad student 2006 University of Washington
Guangtao Zhang grad student 2006 University of Washington
Sayaka Shibata grad student 2011 University of Washington

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Publications

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Zhang Z, Barros-Álvarez X, Gillespie JR, et al. (2020) Structure-guided discovery of selective methionyl-tRNA synthetase inhibitors with potent activity against . Rsc Medicinal Chemistry. 11: 885-895
Michaels SA, Shih HW, Zhang B, et al. (2020) Methionyl-tRNA synthetase inhibitor has potent in vivo activity in a novel Giardia lamblia luciferase murine infection model. The Journal of Antimicrobial Chemotherapy
Barrett KF, Dranow DM, Phan I, et al. (2020) Structures of glyceraldehyde 3-phosphate dehydrogenase in Neisseria gonorrhoeae and Chlamydia trachomatis. Protein Science : a Publication of the Protein Society
Buckner FS, Ranade RM, Gillespie JR, et al. (2019) Optimization of methionyl tRNA-synthetase inhibitors for treatment of infection. Antimicrobial Agents and Chemotherapy
Barrett K, Michaels S, Navaluna E, et al. (2019) P316 Structure-based drug design for neisseria gonorrhoeae, chlamydia trachomatis, and mycoplasma genitalium Sexually Transmitted Infections. 95
Hulverson MA, Bruzual I, McConnell EV, et al. (2018) Pharmacokinetics and In Vivo Efficacy of Pyrazolopyrimidine, Pyrrolopyrimidine and 5-Aminopyrazole-4-Carboximide Bumped Kinase Inhibitors against Toxoplasmosis. The Journal of Infectious Diseases
Barros-Álvarez X, Turley S, Ranade RM, et al. (2018) The crystal structure of the drug target Mycobacterium tuberculosis methionyl-tRNA synthetase in complex with a catalytic intermediate. Acta Crystallographica. Section F, Structural Biology Communications. 74: 245-254
Herbst ZM, Shibata S, Fan E, et al. (2018) An Inexpensive, In-House-Made, Microdialysis Device for Measuring Drug-Protein Binding. Acs Medicinal Chemistry Letters. 9: 279-282
Vidadala RSR, Golkowski M, Hulverson MA, et al. (2018) 7H-pyrrolo[2,3-d]pyrimidin-4-amine based inhibitors of calcium dependent protein kinase 1 have distinct inhibitory and oral pharmacokinetic characteristics compared with 1H-pyrazolo[3,4-d]pyrimidin-4-amine based inhibitors. Acs Infectious Diseases
Jiménez-Meléndez A, Ojo KK, Wallace AM, et al. (2017) In vitro efficacy of bumped kinase inhibitors against Besnoitia besnoiti tachyzoites. International Journal For Parasitology
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