Amanda J. Pickard, Ph.D.
Affiliations: | 2014 | Chemistry | Wake Forest University, Winston-Salem, NC, United States |
Area:
Molecular Chemistry, Oncology, PharmacologyGoogle:
"Amanda Pickard"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Ulrich Bierbach | grad student | 2014 | Wake Forest | |
| (Novel approaches for controlling target selectivity and pharmacological properties of platinum--intercalator-based anticancer agents.) | ||||
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Publications
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| Green AT, Pickard AJ, Li R, et al. (2022) Computational and Experimental Characterization of rDNA and rRNA G-Quadruplexes. The Journal of Physical Chemistry. B |
| Colosimo DA, Kohn JA, Luo PM, et al. (2019) Mapping Interactions of Microbial Metabolites with Human G-Protein-Coupled Receptors. Cell Host & Microbe |
| Cohen LJ, Esterhazy D, Kim SH, et al. (2017) Commensal bacteria make GPCR ligands that mimic human signalling molecules. Nature |
| Yang M, Pickard AJ, Qiao X, et al. (2015) Synthesis, reactivity, and biological activity of gold(I) complexes modified with thiourea-functionalized tyrosine kinase inhibitors. Inorganic Chemistry. 54: 3316-24 |
| Ding S, Pickard AJ, Kucera GL, et al. (2014) Design of enzymatically cleavable prodrugs of a potent platinum-containing anticancer agent. Chemistry (Weinheim An Der Bergstrasse, Germany). 20: 16164-73 |
| Pickard AJ, Liu F, Bartenstein TF, et al. (2014) Redesigning the DNA-targeted chromophore in platinum-acridine anticancer agents: a structure-activity relationship study. Chemistry (Weinheim An Der Bergstrasse, Germany). 20: 16174-87 |
| Pickard AJ, Bierbach U. (2013) The cell's nucleolus: an emerging target for chemotherapeutic intervention. Chemmedchem. 8: 1441-9 |
| Kostrhunova H, Malina J, Pickard AJ, et al. (2011) Replacement of a thiourea with an amidine group in a monofunctional platinum-acridine antitumor agent. Effect on DNA interactions, DNA adduct recognition and repair. Molecular Pharmaceutics. 8: 1941-54 |