Shalini T. Low-Nam, Ph.D.
Affiliations: | 2011 | Biomedical Sciences | University of New Mexico, Albuquerque, NM, United States |
| 2019- | Purdue University, West Lafayette, IN, United States |
Area:
General Biophysics, Cell Biology, BiochemistryWebsite:
https://www.chem.purdue.edu/activity/public/profile/chem/slownamGoogle:
"Shalini Low-Nam"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Diane S. Lidke | grad student | 2011 | Univ. of New Mexico | |
| (Live cell kinetics of ERBB dimerization reveals influences of activation state and membrane organization.) | ||||
| Adam D. Hoppe | post-doc | 2011-2014 | South Dakota State University (Microtree) | |
| Jay T. Groves | post-doc | 2014-2019 | UC Berkeley | |
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Publications
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| Huang L, Thiex NW, Lou J, et al. (2024) The ubiquitin ligases Cbl and Cbl-b regulate macrophage growth by controlling CSF-1R import into macropinosomes. Molecular Biology of the Cell. mbcE23090345 |
| McAffee DB, O'Dair MK, Lin JJ, et al. (2022) Discrete LAT condensates encode antigen information from single pMHC:TCR binding events. Nature Communications. 13: 7446 |
| Lin JJ, O'Donoghue GP, Wilhelm KB, et al. (2020) Membrane Association Transforms an Inert Anti-TCRβ Fab' Ligand into a Potent T Cell Receptor Agonist. Biophysical Journal |
| McAffee D, Low-Nam S, Lin JJ, et al. (2020) The Formation of Lat Protein Condensates in Response to Single pMHC-TCR Binding Events Biophysical Journal. 118: 247a-248a |
| Lin JJY, Low-Nam ST, Alfieri KN, et al. (2019) Mapping the stochastic sequence of individual ligand-receptor binding events to cellular activation: T cells act on the rare events. Science Signaling. 12 |
| Alvarez S, Huang WY, Monatrice Lam HY, et al. (2019) Total Reconstitution of Receptor-Mediated Ras Activation by SOS in Vitro Reveals Kinetic and Conformational Layers of Regulation in MAPK Signaling Biophysical Journal. 116: 531a-532a |
| McAffee DB, Low-Nam ST, Lin JJ, et al. (2019) Single pMHC:TCR Binding Events Precipitate LAT Assemblies Capable of Spatially Decoupling from the Originating Ligand Biophysical Journal. 116: 531a |
| Wilhelm KB, Coyle MP, O'Donoghue GP, et al. (2019) A Membrane-Activated, Universal T-Cell Receptor Agonist Biophysical Journal. 116: 530a-531a |
| Low-Nam ST, Lin JJ, McAffee DB, et al. (2019) Beyond the TCR, Antigen Discrimination in T Cells Continues in the LAT:GRB2:SOS Protein Condensate Biophysical Journal. 116: 530a |
| Lin JJ, Low-Nam ST, Alvarez SA, et al. (2019) Live and Simultaneous Readout of NFAT and ERK Activation in T Cells Reveals Multiple Dimensions of TCR Signaling Biophysical Journal. 116: 530a |