Hashem A. Dbouk, Ph.D.

Affiliations: 
2013 Molecular Pharmacology Yeshiva University, New York, NY, United States 
Area:
Biochemistry, Molecular Biology
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"Hashem Dbouk"
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Jonathan M. Backer grad student 2013 Yeshiva University
 (Regulation of p110beta signaling and functions by interacting proteins.)
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Publications

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Dbouk HA. (2016) Venous malformations: PIK3CA mutations guide new treatments. Oncotarget
Dbouk HA, Huang CL, Cobb MH. (2016) Hypertension: The Missing WNKs. American Journal of Physiology. Renal Physiology. ajprenal.00358.2015
Salamon RS, Dbouk HA, Collado D, et al. (2015) Identification of the Rab5 binding site in p110β: assays for PI3Kβ binding to Rab5. Methods in Molecular Biology (Clifton, N.J.). 1298: 271-81
Dbouk HA, Weil LM, Perera GK, et al. (2014) Actions of the protein kinase WNK1 on endothelial cells are differentially mediated by its substrate kinases OSR1 and SPAK. Proceedings of the National Academy of Sciences of the United States of America. 111: 15999-6004
Wauson EM, Dbouk HA, Ghosh AB, et al. (2014) G protein-coupled receptors and the regulation of autophagy. Trends in Endocrinology and Metabolism: Tem. 25: 274-82
Vadas O, Dbouk HA, Shymanets A, et al. (2013) Molecular determinants of PI3Kγ-mediated activation downstream of G-protein-coupled receptors (GPCRs). Proceedings of the National Academy of Sciences of the United States of America. 110: 18862-7
Talhouk RS, Fares MB, Rahme GJ, et al. (2013) Context dependent reversion of tumor phenotype by connexin-43 expression in MDA-MB231 cells and MCF-7 cells: role of β-catenin/connexin43 association. Experimental Cell Research. 319: 3065-80
Dbouk HA, Khalil BD, Wu H, et al. (2013) Characterization of a tumor-associated activating mutation of the p110β PI 3-kinase. Plos One. 8: e63833
Dou Z, Pan JA, Dbouk HA, et al. (2013) Class IA PI3K p110β subunit promotes autophagy through Rab5 small GTPase in response to growth factor limitation. Molecular Cell. 50: 29-42
Dbouk HA, Backer JM. (2013) Novel approaches to inhibitor design for the p110β phosphoinositide 3-kinase. Trends in Pharmacological Sciences. 34: 149-53
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