Amber L. Mosley, Ph.D.

Affiliations: 
1999-2004 University of Kentucky, Lexington, KY 
 2004-2010 Stowers Institute for Medical Research, Kansas City, Missouri, Kansas City, MO, United States 
 2010- Biochemistry Indiana Univ. School of Medicine 
Area:
Biochemistry, Molecular Biology, Proteomics
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"Amber Mosley"
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Parents

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Sabire Ozcan grad student 1999-2004 University of Kentucky
 (Glucose regulation of insulin gene expression.)
Michael P. Washburn post-doc 2004-2010 Stowers Instititute for Medical Research
Jerry Lee Workman post-doc 2004-2010 Stowers Institute for Medical Research
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Publications

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Victorino JF, Fox MJ, Smith-Kinnaman WR, et al. (2020) RNA Polymerase II CTD phosphatase Rtr1 fine-tunes transcription termination. Plos Genetics. 16: e1008317
Hunter GO, Fox MJ, Smith-Kinnaman WR, et al. (2016) The phosphatase Rtr1 regulates global levels of serine 5 RNA Polymerase II C-terminal domain phosphorylation and cotranscriptional histone methylation. Molecular and Cellular Biology
Bedard LG, Dronamraju R, Kerschner JL, et al. (2016) Quantitative analysis of dynamic protein interactions during transcription reveals a role for casein kinase II in PAF complex phosphorylation and regulation of H2B monoubiquitylation. The Journal of Biological Chemistry
Fox MJ, Mosley AL. (2016) Rrp6: Integrated roles in nuclear RNA metabolism and transcription termination. Wiley Interdisciplinary Reviews. Rna. 7: 91-104
Simon JM, Parker JS, Liu F, et al. (2015) A Role for Widely Interspaced Zinc Finger (WIZ) in Retention of the G9a Methyltransferase on Chromatin. The Journal of Biological Chemistry. 290: 26088-102
Maganti AV, Maier B, Tersey SA, et al. (2015) Transcriptional activity of the islet β cell factor Pdx1 is augmented by lysine methylation catalyzed by the methyltransferase Set7/9. The Journal of Biological Chemistry. 290: 9812-22
Fox MJ, Gao H, Smith-Kinnaman WR, et al. (2015) The exosome component Rrp6 is required for RNA polymerase II termination at specific targets of the Nrd1-Nab3 pathway. Plos Genetics. 11: e1004999
Ni Z, Xu C, Guo X, et al. (2014) RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation. Nature Structural & Molecular Biology. 21: 686-95
Hsu PL, Yang F, Smith-Kinnaman W, et al. (2014) Rtr1 is a dual specificity phosphatase that dephosphorylates Tyr1 and Ser5 on the RNA polymerase II CTD. Journal of Molecular Biology. 426: 2970-81
Smith-Kinnaman WR, Berna MJ, Hunter GO, et al. (2014) The interactome of the atypical phosphatase Rtr1 in Saccharomyces cerevisiae. Molecular Biosystems. 10: 1730-41
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