Jiyun Liu, Ph.D.
Affiliations: | 2006 | University of Washington, Seattle, Seattle, WA |
Area:
BiochemistryGoogle:
"Jiyun Liu"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Erkang Fan | grad student | 2006 | University of Washington | |
| (Structure based design of inhibitors toward disease related multivalent protein targets.) | ||||
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Publications
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| Li Z, Scott MJ, Fan EK, et al. (2016) Tissue damage negatively regulates LPS-induced macrophage necroptosis. Cell Death and Differentiation |
| Koh CY, Kim JE, Wetzel AB, et al. (2014) Structures of Trypanosoma brucei methionyl-tRNA synthetase with urea-based inhibitors provide guidance for drug design against sleeping sickness. Plos Neglected Tropical Diseases. 8: e2775 |
| Koh CY, Kim JE, Shibata S, et al. (2012) Distinct states of methionyl-tRNA synthetase indicate inhibitor binding by conformational selection. Structure (London, England : 1993). 20: 1681-91 |
| Liu J, Begley D, Mitchell DD, et al. (2008) Multivalent drug design and inhibition of cholera toxin by specific and transient protein-ligand interactions. Chemical Biology & Drug Design. 71: 408-19 |
| Liu J, Zhang Z, Tan X, et al. (2005) Protein heterodimerization through ligand-bridged multivalent pre-organization: enhancing ligand binding toward both protein targets. Journal of the American Chemical Society. 127: 2044-5 |
| Zhang Z, Liu J, Verlinde CL, et al. (2004) Large cyclic peptides as cores of multivalent ligands: application to inhibitors of receptor binding by cholera toxin. The Journal of Organic Chemistry. 69: 7737-40 |
| Pickens JC, Mitchell DD, Liu J, et al. (2004) Nonspanning bivalent ligands as improved surface receptor binding inhibitors of the cholera toxin B pentamer. Chemistry & Biology. 11: 1205-15 |