Alessandro Bitto, Ph.D.
Affiliations: | 2013 | Pathology | Drexel University College of Medicine, Philadelphia, PA, United States |
Area:
Cell BiologyGoogle:
"Alessandro Bitto"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Christian Sell | grad student | 2013 | Drexel Medical School | |
| (The mammalian Target of Rapamycin regulates mitochondrial homeostasis and cellular senescence through the autophagy adaptor of p62/SQSTM1.) | ||||
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Publications
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| Bitto A, Grillo AS, Ito TK, et al. (2023) Acarbose suppresses symptoms of mitochondrial disease in a mouse model of Leigh syndrome. Nature Metabolism. 5: 955-967 |
| Whitson JA, Johnson R, Wang L, et al. (2022) Age-related disruption of the proteome and acetylome in mouse hearts is associated with loss of function and attenuated by elamipretide (SS-31) and nicotinamide mononucleotide (NMN) treatment. Geroscience |
| Grillo AS, Bitto A, Kaeberlein M. (2021) The NDUFS4 Knockout Mouse: A Dual Threat Model of Childhood Mitochondrial Disease and Normative Aging. Methods in Molecular Biology (Clifton, N.J.). 2277: 143-155 |
| Whitson JA, Bitto A, Zhang H, et al. (2020) SS-31 and NMN: Two paths to improve metabolism and function in aged hearts. Aging Cell. e13213 |
| Johnson SC, Kayser EB, Bornstein R, et al. (2020) Regional metabolic signatures in the Ndufs4(KO) mouse brain implicate defective glutamate/α-ketoglutarate metabolism in mitochondrial disease. Molecular Genetics and Metabolism |
| Bitto A, Tung H, Ying K, et al. (2019) Aging And Mitochondrial Disease: Shared Mechanisms And Therapies? Innovation in Aging. 3 |
| Bitto A. (2019) Is Aging An Acquired Mitochondrial Disease Innovation in Aging. 3 |
| Johnson SC, Martinez F, Bitto A, et al. (2018) mTOR inhibitors may benefit kidney transplant recipients with mitochondrial diseases. Kidney International |
| Ito TK, Lu C, Khan J, et al. (2017) Corrigendum: Hepatic S6K1 Partially Regulates Lifespan of Mice with Mitochondrial Complex I Deficiency. Frontiers in Genetics. 8: 221 |
| Ito TK, Lu C, Khan J, et al. (2017) Hepatic S6K1 Partially Regulates Lifespan of Mice with Mitochondrial Complex I Deficiency. Frontiers in Genetics. 8: 113 |