Sanju Narayanan, Ph.D.

Affiliations: 
2009 The University of Mississippi, USA 
Area:
Pharmaceutical Chemistry
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"Sanju Narayanan"
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Christopher R. McCurdy grad student 2009 The University of Mississippi
 (Design, synthesis and biological evaluation of novel selective sigma -2 receptor ligands.)
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Publications

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Narayanan S, Dai D, Vyas Devambatla RK, et al. (2022) Synthesis and characterization of an orally bioavailable small molecule agonist of the apelin receptor. Bioorganic & Medicinal Chemistry. 66: 116789
Narayanan S, Wang S, Vasukuttan V, et al. (2021) Pyrazole Agonist of the Apelin Receptor Improves Symptoms of Metabolic Syndrome in Mice. Journal of Medicinal Chemistry
Narayanan S, Vasukuttan V, Rajagopal S, et al. (2019) Identification of potent pyrazole based APELIN receptor (APJ) agonists. Bioorganic & Medicinal Chemistry. 115237
Narayanan S, Maitra R, Deschamps JR, et al. (2016) Discovery of a novel small molecule agonist scaffold for the APJ receptor. Bioorganic & Medicinal Chemistry
Katz JL, Hiranita T, Kopajtic TA, et al. (2016) Blockade of Cocaine or Sigma Receptor Agonist Self-Administration by Subtype- Selective Sigma Receptor Antagonists. The Journal of Pharmacology and Experimental Therapeutics
Thomas JB, Giddings AM, Olepu S, et al. (2015) Identification of N-{[6-chloro-4-(2,6-dimethoxyphenyl)quinazolin-2-yl]carbonyl}-l-leucine (NTRC-808), a novel nonpeptide chemotype selective for the neurotensin receptor type 2. Bioorganic & Medicinal Chemistry Letters. 25: 292-6
Buzard DJ, Kim SH, Lehmann J, et al. (2014) Discovery and optimization of 5-fluoro-4,6-dialkoxypyrimidine GPR119 agonists. Bioorganic & Medicinal Chemistry Letters. 24: 4332-5
Kaushal N, Robson MJ, Vinnakota H, et al. (2011) Synthesis and pharmacological evaluation of 6-acetyl-3-(4-(4-(4-fluorophenyl)piperazin-1-yl)butyl)benzo[d]oxazol-2(3H)-one (SN79), a cocaine antagonist, in rodents. The Aaps Journal. 13: 336-46
Narayanan S, Bhat R, Mesangeau C, et al. (2011) Early development of sigma-receptor ligands. Future Medicinal Chemistry. 3: 79-94
Narayanan S, Mesangeau C, Poupaert JH, et al. (2011) Sigma receptors and cocaine abuse. Current Topics in Medicinal Chemistry. 11: 1128-50
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