Poulami Samai, Ph.D.

Affiliations: 
2012 Weill Cornell Medical College, New York, NY, United States 
Area:
Biochemistry, Molecular Biology
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"Poulami Samai"
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Parents

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Stewart Shuman grad student 2012 Weill Cornell Medical College
 (Lessons in Ligation: Structure -- Function Studies of a Minimal Pluripotent DNA Ligase.)
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Publications

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Jiang W, Samai P, Marraffini LA. (2016) Degradation of Phage Transcripts by CRISPR-Associated RNases Enables Type III CRISPR-Cas Immunity. Cell
Samai P, Pyenson N, Jiang W, et al. (2015) Co-transcriptional DNA and RNA Cleavage during Type III CRISPR-Cas Immunity. Cell. 161: 1164-74
Heler R, Samai P, Modell JW, et al. (2015) Cas9 specifies functional viral targets during CRISPR-Cas adaptation. Nature. 519: 199-202
Hatoum-Aslan A, Maniv I, Samai P, et al. (2014) Genetic characterization of antiplasmid immunity through a type III-A CRISPR-Cas system. Journal of Bacteriology. 196: 310-7
Hatoum-Aslan A, Samai P, Maniv I, et al. (2013) A ruler protein in a complex for antiviral defense determines the length of small interfering CRISPR RNAs. The Journal of Biological Chemistry. 288: 27888-97
Bikard D, Jiang W, Samai P, et al. (2013) Programmable repression and activation of bacterial gene expression using an engineered CRISPR-Cas system. Nucleic Acids Research. 41: 7429-37
Samai P, Shuman S. (2012) Kinetic analysis of DNA strand joining by Chlorella virus DNA ligase and the role of nucleotidyltransferase motif VI in ligase adenylylation. The Journal of Biological Chemistry. 287: 28609-18
Samai P, Shuman S. (2011) Structure-function analysis of the OB and latch domains of chlorella virus DNA ligase. The Journal of Biological Chemistry. 286: 22642-52
Samai P, Shuman S. (2011) Functional dissection of the DNA interface of the nucleotidyltransferase domain of chlorella virus DNA ligase. The Journal of Biological Chemistry. 286: 13314-26
Samai P, Smith P, Shuman S. (2010) Structure of a CRISPR-associated protein Cas2 from Desulfovibrio vulgaris. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 1552-6
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