Shujun Yuan, Ph.D.

Affiliations: 
2009 Boston University, Boston, MA, United States 
Area:
General Biophysics
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"Shujun Yuan"
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Parents

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Christopher Winslow Akey grad student 2009 Boston University
 (Structural and functional studies of the human apoptosome.)
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Publications

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Zhao XY, Wilmen A, Wang D, et al. (2020) Targeted inhibition of activated protein C by a non-active-site inhibitory antibody to treat hemophilia. Nature Communications. 11: 2992
Cheng TC, Akey IV, Yuan S, et al. (2017) A Near-Atomic Structure of the Dark Apoptosome Provides Insight into Assembly and Activation. Structure (London, England : 1993). 25: 40-52
Cheng TC, Hong C, Akey IV, et al. (2016) A near atomic structure of the active human apoptosome. Elife. 5
Cheng TC, Hong C, Akey IV, et al. (2016) Author response: A near atomic structure of the active human apoptosome Elife
D'Brot A, Chen P, Vaishnav M, et al. (2013) Tango7 directs cellular remodeling by the Drosophila apoptosome. Genes & Development. 27: 1650-5
Yuan S, Akey CW. (2013) Apoptosome structure, assembly, and procaspase activation. Structure (London, England : 1993). 21: 501-15
Yuan S, Topf M, Reubold TF, et al. (2013) Changes in Apaf-1 conformation that drive apoptosome assembly. Biochemistry. 52: 2319-27
Yuan S, Yu X, Asara JM, et al. (2011) The holo-apoptosome: activation of procaspase-9 and interactions with caspase-3. Structure (London, England : 1993). 19: 1084-96
Yuan S, Yu X, Topf M, et al. (2011) Structure of the Drosophila apoptosome at 6.9 å resolution. Structure (London, England : 1993). 19: 128-40
Yuan S, Yu X, Topf M, et al. (2011) Structure of the Drosophila apoptosome at 6.9 angstrom resolution Structure. 19: 128-140
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