Jeremiah D. Farelli, Ph.D.

Affiliations: 
2010 Boston University, Boston, MA, United States 
Area:
General Biophysics, Microbiology Biology, Molecular Biology
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"Jeremiah Farelli"
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Christopher Winslow Akey grad student 2010 Boston University
 (Crystal structure of the ICMR-ICMG complex: Implications for a type IVB secretion system in Legionella pneumophila.)
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Publications

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Huang H, Pandya C, Liu C, et al. (2015) Panoramic view of a superfamily of phosphatases through substrate profiling. Proceedings of the National Academy of Sciences of the United States of America. 112: E1974-83
London N, Farelli JD, Brown SD, et al. (2015) Covalent docking predicts substrates for haloalkanoate dehalogenase superfamily phosphatases. Biochemistry. 54: 528-37
Pandya C, Farelli JD, Dunaway-Mariano D, et al. (2014) Enzyme promiscuity: engine of evolutionary innovation. The Journal of Biological Chemistry. 289: 30229-36
Wu R, Latham JA, Chen D, et al. (2014) Structure and catalysis in the Escherichia coli hotdog-fold thioesterase paralogs YdiI and YbdB. Biochemistry. 53: 4788-805
Farelli JD, Galvin BD, Li Z, et al. (2014) Structure of the trehalose-6-phosphate phosphatase from Brugia malayi reveals key design principles for anthelmintic drugs. Plos Pathogens. 10: e1004245
Barelier S, Cummings JA, Rauwerdink AM, et al. (2014) Substrate deconstruction and the nonadditivity of enzyme recognition. Journal of the American Chemical Society. 136: 7374-82
Farelli JD, Gumbart JC, Akey IV, et al. (2013) IcmQ in the Type 4b secretion system contains an NAD+ binding domain. Structure (London, England : 1993). 21: 1361-73
Chen D, Latham J, Zhao H, et al. (2012) Human brown fat inducible thioesterase variant 2 cellular localization and catalytic function. Biochemistry. 51: 6990-9
Brown JW, Farelli JD, McKnight CJ. (2012) On the unyielding hydrophobic core of villin headpiece. Protein Science : a Publication of the Protein Society. 21: 647-54
Brown JW, Farelli JD, McKnight CJ. (2011) On unsatisfied hydrogen bonds in the N-terminal subdomain of villin headpiece. Journal of Molecular Biology. 413: 543-7
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