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Brigham B. Hyde, Ph.D.

Affiliations: 
2009 Pharmacology & Experimental Therapeutics Sackler School of Graduate Biomedical Sciences (Tufts University) 
Area:
Pharmacology, Cell Biology, Oncology
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Theoharis C. Theoharides grad student 2009 Sackler School of Graduate Biomedical Sciences (Tufts University)
 (The role of ABCme in hematopoiesis and mitochondrial oxidative stress.)

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Publications

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Hyde BB, Liesa M, Elorza AA, et al. (2012) The mitochondrial transporter ABC-me (ABCB10), a downstream target of GATA-1, is essential for erythropoiesis in vivo. Cell Death and Differentiation. 19: 1117-26
Liesa M, Luptak I, Qin F, et al. (2011) Mitochondrial transporter ATP binding cassette mitochondrial erythroid is a novel gene required for cardiac recovery after ischemia/reperfusion. Circulation. 124: 806-13
Hyde BB, Twig G, Shirihai OS. (2010) Organellar vs cellular control of mitochondrial dynamics. Seminars in Cell & Developmental Biology. 21: 575-81
Chen W, Paradkar PN, Li L, et al. (2009) Abcb10 physically interacts with mitoferrin-1 (Slc25a37) to enhance its stability and function in the erythroid mitochondria. Proceedings of the National Academy of Sciences of the United States of America. 106: 16263-8
Elorza A, Hyde B, Mikkola HK, et al. (2008) UCP2 modulates cell proliferation through the MAPK/ERK pathway during erythropoiesis and has no effect on heme biosynthesis. The Journal of Biological Chemistry. 283: 30461-70
Twig G, Hyde B, Shirihai OS. (2008) Mitochondrial fusion, fission and autophagy as a quality control axis: the bioenergetic view. Biochimica Et Biophysica Acta. 1777: 1092-7
Hyde BB, Elorza AA, Mikkola HK, et al. (2008) ABC-Me (ABCB10) Is Required for Erythroid Development in the Mouse Embryo and Is Protective against Mitochondrial Oxidative Stress Blood. 112: 529-529
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