Srinivas Somarowthu, Ph.D.

2011 Chemistry Northeastern University, Boston, MA, United States 
Physical Chemistry, Biochemistry, Bioinformatics Biology
"Srinivas Somarowthu"
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Penny J. Beuning grad student 2011 Northeastern University
 (Prediction and experimental verification of compact versus extended enzyme active sites: A tale of two isomerases.)
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Yankey A, Clark SC, Owens MC, et al. (2021) Purification and Structural Characterization of the Long Noncoding RNAs. Methods in Molecular Biology (Clifton, N.J.). 2372: 93-110
Mazina OM, Somarowthu S, Kadyrova LY, et al. (2020) Replication protein A binds RNA and promotes R-loop formation. The Journal of Biological Chemistry
Manigrasso J, Chillón I, Genna V, et al. (2020) Visualizing group II intron dynamics between the first and second steps of splicing. Nature Communications. 11: 2837
Owens MC, Clark SC, Yankey A, et al. (2019) Identifying Structural Domains and Conserved Regions in the Long Non-Coding RNA lncTCF7. International Journal of Molecular Sciences. 20
Tavares RCA, Pyle AM, Somarowthu S. (2019) Phylogenetic Analysis with Improved Parameters Reveals Conservation in lncRNA Structures. Journal of Molecular Biology
Liu F, Somarowthu S, Pyle AM. (2017) Visualizing the secondary and tertiary architectural domains of lncRNA RepA. Nature Chemical Biology
Somarowthu S. (2016) Progress and Current Challenges in Modeling Large RNAs. Journal of Molecular Biology. 428: 736-47
Chillon I, Somarowthu S, Liu F, et al. (2016) Abstract IA25: Regulatory control of lincRNA function through formation of complex RNA structural motifs Cancer Research. 76
Chillón I, Marcia M, Legiewicz M, et al. (2015) Native Purification and Analysis of Long RNAs. Methods in Enzymology. 558: 3-37
Somarowthu S, Legiewicz M, Chillón I, et al. (2015) HOTAIR forms an intricate and modular secondary structure. Molecular Cell. 58: 353-61
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