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Richard S. Kang, Ph.D.

Affiliations: 
2011 Interdepartmental Biological Sciences Program Northwestern University, Evanston, IL 
Area:
Cell Biology, Molecular Biology, Biochemistry
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Heike Folsch grad student 2011 Northwestern
 (Autosomal recessive hypercholesterolemia (ARH) protein cooperates with AP-1B in the exocytosis of LDLR in polarized epithelial cells.)

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Publications

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Pigati L, Kang RS, Fölsch H. (2013) Using replication defective viruses to analyze membrane trafficking in polarized epithelial cells. Methods in Cell Biology. 118: 125-37
Cook RN, Ang SF, Kang RS, et al. (2011) Analyzing the function of small GTPases by microinjection of plasmids into polarized epithelial cells. Journal of Visualized Experiments : Jove
Kang RS, Fölsch H. (2011) ARH cooperates with AP-1B in the exocytosis of LDLR in polarized epithelial cells. The Journal of Cell Biology. 193: 51-60
Fields IC, King SM, Shteyn E, et al. (2010) Phosphatidylinositol 3,4,5-trisphosphate localization in recycling endosomes is necessary for AP-1B-dependent sorting in polarized epithelial cells. Molecular Biology of the Cell. 21: 95-105
Kang RS, Fölsch H. (2009) An old dog learns new tricks: novel functions of the exocyst complex in polarized epithelia in animals. F1000 Biology Reports. 1: 83
Sahu SC, Swanson KA, Kang RS, et al. (2008) Conserved themes in target recognition by the PAH1 and PAH2 domains of the Sin3 transcriptional corepressor. Journal of Molecular Biology. 375: 1444-56
Fields IC, Shteyn E, Pypaert M, et al. (2007) v-SNARE cellubrevin is required for basolateral sorting of AP-1B-dependent cargo in polarized epithelial cells. The Journal of Cell Biology. 177: 477-88
Swanson KA, Knoepfler PS, Huang K, et al. (2004) HBP1 and Mad1 repressors bind the Sin3 corepressor PAH2 domain with opposite helical orientations. Nature Structural & Molecular Biology. 11: 738-46
Cowley SM, Kang RS, Frangioni JV, et al. (2004) Functional analysis of the Mad1-mSin3A repressor-corepressor interaction reveals determinants of specificity, affinity, and transcriptional response. Molecular and Cellular Biology. 24: 2698-709
Swanson KA, Kang RS, Stamenova SD, et al. (2003) Solution structure of Vps27 UIM-ubiquitin complex important for endosomal sorting and receptor downregulation. The Embo Journal. 22: 4597-606
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