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Joshua Rokach

Affiliations: 
Florida Institute of Technology, Melbourne, FL, United States 
Area:
Biochemistry
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"Joshua Rokach"
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Children

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Seongjin Kim grad student 2001 Florida Institute of Technology
Sheila M. Jacobo grad student 2005 Florida Institute of Technology
Sashikala Sivendran grad student 2005 Florida Institute of Technology
Namin Kang grad student 2007 Florida Institute of Technology
Chih-Tsung Chang grad student 2008 Florida Institute of Technology
Pranav Patel grad student 2008 Florida Institute of Technology
Vivek Gore grad student 2011 Florida Institute of Technology
Qiuji Ye grad student 2012-2018 Florida Institute of Technology

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Publications

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Chourey S, Wang R, Ye Q, et al. (2023) Concise Syntheses of Microsomal Metabolites of a Potent OXE (Oxoeicosanoid) Receptor Antagonist. Chemical & Pharmaceutical Bulletin. 71: 534-544
Cossette C, Chourey S, Ye Q, et al. (2022) Metabolism of anti-inflammatory OXE (oxoeicosanoid) receptor antagonists by nonhuman primates. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 106144
Cossette C, Miller LA, Ye Q, et al. (2021) Targeting the oxoeicosanoid (OXE) receptor with a selective antagonist inhibits allergen-induced pulmonary inflammation in non-human primates. British Journal of Pharmacology
Powell WS, Rokach J. (2020) Targeting the OXE receptor as a potential novel therapy for asthma. Biochemical Pharmacology. 113930
Ye Q, Chourey S, Reddy CN, et al. (2019) Novel highly potent OXE receptor antagonists with prolonged plasma lifetimes that are converted to active metabolites in vivo in monkeys. British Journal of Pharmacology
Miller LA, Cossette C, Chourey S, et al. (2019) Inhibition of allergen-induced dermal eosinophilia by an oxoeicosanoid (OXE) receptor antagonist in nonhuman primates. British Journal of Pharmacology
Chourey S, Ye Q, Reddy CN, et al. (2018) Novel highly potent and metabolically resistant oxoeicosanoid (OXE) receptor antagonists that block the actions of the granulocyte chemoattractant 5-oxo-6,8,11,14-eicosatetraenoic acid (5-oxo-ETE). Journal of Medicinal Chemistry
Chourey S, Ye Q, Reddy CN, et al. (2018) Corrigendum to "In vivo α-hydroxylation of a 2-alkylindole antagonist of the OXE receptor for the eosinophil chemoattractant 5-oxo-6,8,11,14-eicosatetraenoic acid in monkeys" [Biochem. Pharmacol. 138 (2017) 107-118]. Biochemical Pharmacology. 154: 174
Reddy CN, Alhamza H, Chourey S, et al. (2018) Metabolism and pharmacokinetics of a potent N-acylindole antagonist of the OXE receptor for the eosinophil chemoattractant 5-oxo-6,8,11,14-eicosatetraenoic acid (5-oxo-ETE) in rats and monkeys. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences
Ye Q, Chourey S, Wang R, et al. (2017) Structure-activity relationship study of β-oxidation resistant indole-based 5-oxo-6,8,11,14-eicosatetraenoic acid (5-oxo-ETE) receptor antagonists. Bioorganic & Medicinal Chemistry Letters
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