Clapton S. Dias, Ph.D.

Affiliations: 
2002 University of Missouri - Kansas City, USA 
Area:
Pharmacy
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"Clapton Dias"
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Ashim K. Mitra grad student 2002 University of Missouri - Kansas City
 (Enhanced ocular bioavailability of acycloguanosine analogs via prodrug approaches and rabbit models to determine ocular pharmacokinetics of drugs.)
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Publications

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Dias CS, Mitra AK. (2003) Posterior segment ocular pharmacokinetics using microdialysis in a conscious rabbit model. Investigative Ophthalmology & Visual Science. 44: 300-5
Dias C, Nashed Y, Atluri H, et al. (2002) Ocular penetration of acyclovir and its peptide prodrugs valacyclovir and val-valacyclovir following systemic administration in rabbits: An evaluation using ocular microdialysis and LC-MS. Current Eye Research. 25: 243-52
Tirucherai GS, Dias C, Mitra AK. (2002) Corneal permeation of ganciclovir: mechanism of ganciclovir permeation enhancement by acyl ester prodrug design. Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association For Ocular Pharmacology and Therapeutics. 18: 535-48
Dias CS, Anand BS, Mitra AK. (2002) Effect of mono- and di-acylation on the ocular disposition of ganciclovir: physicochemical properties, ocular bioreversion, and antiviral activity of short chain ester prodrugs. Journal of Pharmaceutical Sciences. 91: 660-8
Dias CS, Mitra AK. (2000) Vitreal elimination kinetics of large molecular weight FITC-labeled dextrans in albino rabbits using a novel microsampling technique. Journal of Pharmaceutical Sciences. 89: 572-8
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