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Aswani D. Vadlapudi, Ph.D.

Affiliations: 
2013 Pharmaceutical Science University of Missouri - Kansas City, USA 
Area:
Pharmacy, Organic Chemistry
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Ashim K. Mitra grad student 2013 University of Missouri - Kansas City
 (Novel targeted lipid prodrugs to improve cellular absorption of acyclovir and topical delivery to the eye via nanomicellar approach.)

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Publications

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Cholkar K, Trinh HM, Vadlapudi AD, et al. (2015) Interaction Studies of Resolvin E1 Analog (RX-10045) with Efflux Transporters. Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association For Ocular Pharmacology and Therapeutics. 31: 248-55
Khurana V, Vadlapudi AD, Vadlapatla RK, et al. (2015) Functional characterization and molecular identification of vitamin C transporter (SVCT2) in human corneal epithelial (HCEC) and retinal pigment epithelial (D407) cells. Current Eye Research. 40: 457-69
Mitra A, Renukuntla J, Shah S, et al. (2015) Functional characterization and expression of folate receptor-α in T47D human breast cancer cells Drug Development and Therapeutics. 6: 52
Cholkar K, Trinh HM, Vadlapudi AD, et al. (2014) Synthesis and Characterization of Ganciclovir Long Chain Lipid Prodrugs. Advances in Ophthalmology & Visual System. 1
Vadlapatla RK, Vadlapudi AD, Pal D, et al. (2014) Role of membrane transporters and metabolizing enzymes in ocular drug delivery. Current Drug Metabolism. 15: 680-93
Kwatra D, Vadlapudi AD, Vadlapatla RK, et al. (2014) Binary and ternary combinations of anti-HIV protease inhibitors: effect on gene expression and functional activity of CYP3A4 and efflux transporters. Drug Metabolism and Drug Interactions. 29: 101-10
Vadlapatla RK, Vadlapudi AD, Pal D, et al. (2014) Ritonavir inhibits HIF-1α-mediated VEGF expression in retinal pigment epithelial cells in vitro. Eye (London, England). 28: 93-101
Vadlapudi AD, Cholkar K, Vadlapatla RK, et al. (2014) Aqueous nanomicellar formulation for topical delivery of biotinylated lipid prodrug of acyclovir: formulation development and ocular biocompatibility. Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association For Ocular Pharmacology and Therapeutics. 30: 49-58
Vadlapatla RK, Vadlapudi AD, Pal D, et al. (2013) Mechanisms of drug resistance in cancer chemotherapy: coordinated role and regulation of efflux transporters and metabolizing enzymes. Current Pharmaceutical Design. 19: 7126-40
Vadlapatla RK, Vadlapudi AD, Ponnaluri VK, et al. (2013) Molecular expression and functional activity of efflux and influx transporters in hypoxia induced retinal pigment epithelial cells. International Journal of Pharmaceutics. 454: 444-52
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