Wang-Yong Yang, Ph.D.

Affiliations: 
2011 Florida State University, Tallahassee, FL, United States 
Area:
Organic Chemistry, Biochemistry
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"Wang-Yong Yang"
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Parents

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Igor V. Alabugin grad student 2011 Florida State
 (Design of pH-controlled light-activated reagents for efficient cleavage of double-stranded DNA and cancer phototherapy.)
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Publications

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Yang WY, He F, Strack RL, et al. (2016) Small Molecule Recognition and Tools to Study Modulation of r(CGG)exp in Fragile X-Associated Tremor Ataxia Syndrome. Acs Chemical Biology
Haga CL, Velagapudi SP, Strivelli JR, et al. (2015) Small Molecule Inhibition of miR-544 Biogenesis Disrupts Adaptive Responses to Hypoxia by Modulating ATM-mTOR Signaling. Acs Chemical Biology
Yang WY, Wilson HD, Velagapudi SP, et al. (2015) Inhibition of Non-ATG Translational Events in Cells via Covalent Small Molecules Targeting RNA. Journal of the American Chemical Society. 137: 5336-45
Su Z, Zhang Y, Gendron TF, et al. (2014) Discovery of a biomarker and lead small molecules to target r(GGGGCC)-associated defects in c9FTD/ALS. Neuron. 83: 1043-50
Colak D, Zaninovic N, Cohen MS, et al. (2014) Promoter-bound trinucleotide repeat mRNA drives epigenetic silencing in fragile X syndrome. Science (New York, N.Y.). 343: 1002-5
Disney MD, Liu B, Yang WY, et al. (2012) A small molecule that targets r(CGG)(exp) and improves defects in fragile X-associated tremor ataxia syndrome. Acs Chemical Biology. 7: 1711-8
Breiner B, Kaya K, Roy S, et al. (2012) Hybrids of amino acids and acetylenic DNA-photocleavers: optimising efficiency and selectivity for cancer phototherapy. Organic & Biomolecular Chemistry. 10: 3974-87
Yang WY, Roy S, Phrathep B, et al. (2011) Engineering pH-gated transitions for selective and efficient double-strand DNA photocleavage in hypoxic tumors. Journal of Medicinal Chemistry. 54: 8501-16
Yang WY, Marrone SA, Minors N, et al. (2011) Fine-tuning alkyne cycloadditions: Insights into photochemistry responsible for the double-strand DNA cleavage via structural perturbations in diaryl alkyne conjugates. Beilstein Journal of Organic Chemistry. 7: 813-23
Yang WY, Cao Q, Callahan C, et al. (2010) Intracellular DNA damage by lysine-acetylene conjugates. Journal of Nucleic Acids. 2010
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