Mark M. Yore, Ph.D.
Affiliations: | 2010 | Pharmacology and Toxicology | Dartmouth College, Hanover, NH, United States |
Area:
Molecular Biology, BiochemistryGoogle:
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Parents
Sign in to add mentorMichael B. Sporn | grad student | 2010 | Dartmouth | |
(The identification of molecular targets of synthetic oleanane triterpenoids.) |
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Publications
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Syed I, Lee J, Moraes-Vieira PM, et al. (2018) Palmitic Acid Hydroxystearic Acids Activate GPR40, Which Is Involved in Their Beneficial Effects on Glucose Homeostasis. Cell Metabolism. 27: 419-427.e4 |
Yore MM, Syed I, Moraes-Vieira PM, et al. (2014) Discovery of a class of endogenous mammalian lipids with anti-diabetic and anti-inflammatory effects. Cell. 159: 318-32 |
Moraes-Vieira PM, Yore MM, Dwyer PM, et al. (2014) RBP4 activates antigen-presenting cells, leading to adipose tissue inflammation and systemic insulin resistance. Cell Metabolism. 19: 512-26 |
Norseen J, Hosooka T, Hammarstedt A, et al. (2012) Retinol-binding protein 4 inhibits insulin signaling in adipocytes by inducing proinflammatory cytokines in macrophages through a c-Jun N-terminal kinase- and toll-like receptor 4-dependent and retinol-independent mechanism. Molecular and Cellular Biology. 32: 2010-9 |
Yore MM, Kettenbach AN, Sporn MB, et al. (2011) Proteomic analysis shows synthetic oleanane triterpenoid binds to mTOR. Plos One. 6: e22862 |
Sporn MB, Liby KT, Yore MM, et al. (2011) New synthetic triterpenoids: Potent agents for prevention and treatment of tissue injury caused by inflammatory and oxidative stress Journal of Natural Products. 74: 537-545 |
Liby K, Risingsong R, Royce DB, et al. (2009) Triterpenoids CDDO-methyl ester or CDDO-ethyl amide and rexinoids LG100268 or NRX194204 for prevention and treatment of lung cancer in mice. Cancer Prevention Research (Philadelphia, Pa.). 2: 1050-8 |
Liby K, Yore MM, Roebuck BD, et al. (2008) A novel acetylenic tricyclic bis-(cyano enone) potently induces phase 2 cytoprotective pathways and blocks liver carcinogenesis induced by aflatoxin Cancer Research. 68: 6727-6733 |
Liby K, Risingsong R, Royce DB, et al. (2008) Prevention and treatment of experimental estrogen receptor- negative mammary carcinogenesis by the synthetic triterpenoid CDDO-methyl ester and the rexinoid LG100268 Clinical Cancer Research. 14: 4556-4563 |
Liby K, Black CC, Royce DB, et al. (2008) The rexinoid LG100268 and the synthetic triterpenoid CDDO-methyl amide are more potent than erlotinib for prevention of mouse lung carcinogenesis Molecular Cancer Therapeutics. 7: 1251-1257 |